Carotenoids: biochemistry, pharmacology and treatment

A Milani, M Basirnejad, S Shahbazi… - British journal of …, 2017 - Wiley Online Library
Carotenoids and retinoids have several similar biological activities such as antioxidant
properties, the inhibition of malignant tumour growth and the induction of apoptosis …

The role of oxidative stress and its counteractive utility in colorectal cancer (CRC)

D Basak, MN Uddin, J Hancock - Cancers, 2020 - mdpi.com
Simple Summary Colorectal cancer (CRC) is very common throughout the world. Despite an
improved outcome with the current treatment regimen, a huge number of patients relapse …

Curcumin encapsulation in functional PLGA nanoparticles: A promising strategy for cancer therapies

F da Silva Feltrin, T Agner, C Sayer… - Advances in colloid and …, 2022 - Elsevier
Nanoparticles have emerged as promising drug delivery systems for the treatment of several
diseases. Novel cancer therapies have exploited these particles as alternative adjuvant …

[HTML][HTML] Nanoformulations of curcumin: an emerging paradigm for improved remedial application

M Gera, N Sharma, M Ghosh, SJ Lee, T Min, T Kwon… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Curcumin is a natural polyphenol and essential curcuminoid derived from the rhizome of the
medicinal plant Curcuma longa (L.) is universally acknowledged as “Wonder drug of life”. It …

Sp1 transcription factor: A long-standing target in cancer chemotherapy

C Vizcaíno, S Mansilla, J Portugal - Pharmacology & therapeutics, 2015 - Elsevier
Abstract Sp1 (specificity protein 1) is a well-known member of a family of transcription factors
that also includes Sp2, Sp3 and Sp4, which are implicated in an ample variety of essential …

Potential anticancer properties and mechanisms of action of curcumin

NG Vallianou, A Evangelopoulos, N Schizas… - Anticancer …, 2015 - ar.iiarjournals.org
Curcumin, a yellow substance belonging to the polyphenols superfamily, is the active
component of turmeric, a common Indian spice, which is derived from the dried rhizome of …

Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?

J Ravindran, S Prasad, BB Aggarwal - The AAPS journal, 2009 - Springer
Cancer is a hyperproliferative disorder that is usually treated by chemotherapeutic agents
that are toxic not only to tumor cells but also to normal cells, so these agents produce major …

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

BB Aggarwal, B Sung - Trends in pharmacological sciences, 2009 - cell.com
Curcumin (diferuloylmethane), a yellow pigment in the spice turmeric (also called curry
powder), has been used for centuries as a treatment for inflammatory diseases. Extensive …

Curcumin overcome primary gefitinib resistance in non-small-cell lung cancer cells through inducing autophagy-related cell death

P Chen, HP Huang, Y Wang, J Jin, WG Long… - Journal of Experimental …, 2019 - Springer
Background Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are
being wildly used as target therapy in non-small-cell lung cancer (NSCLC). However …

Curcumin in various cancers

A Shehzad, J Lee, YS Lee - Biofactors, 2013 - Wiley Online Library
Curcumin (diferuloylmethane), an active constituent of turmeric, is a well‐described
phytochemical, which has been used since ancient times for the treatment of various …