Delivery of nanoparticle-based radiosensitizers for radiotherapy applications

F Boateng, W Ngwa - International journal of molecular sciences, 2019 - mdpi.com
Nanoparticle-based radiosensitization of cancerous cells is evolving as a favorable modality
for enhancing radiotherapeutic ratio, and as an effective tool for increasing the outcome of …

Radiosensitization by gold nanoparticles: Will they ever make it to the clinic?

L Cui, S Her, GR Borst, RG Bristow, DA Jaffray… - Radiotherapy and …, 2017 - Elsevier
The utilization of gold nanoparticles (AuNPs) as radiosensitizers has shown great promise in
pre-clinical research. In the current review, the physical, chemical, and biological pathways …

Progress in research on gold nanoparticles in cancer management

J Peng, X Liang - Medicine, 2019 - journals.lww.com
Conclusion: AuNPs have many properties that are of great value for the diagnosis and
treatment of tumors. AuNPs are small in size and can penetrate widely and deposit on the …

Targeted radiotherapy with gold nanoparticles: current status and future perspectives

W Ngwa, R Kumar, S Sridhar, H Korideck… - …, 2014 - Taylor & Francis
Radiation therapy (RT) is the treatment of cancer and other diseases with ionizing radiation.
The ultimate goal of RT is to destroy all the disease cells while sparing healthy tissue …

Nanoparticle location and material-dependent dose enhancement in X-ray radiation therapy

M Hossain, M Su - The Journal of Physical Chemistry C, 2012 - ACS Publications
Nanoparticles of high atomic number (Z) materials can act as radiosensitizers to enhance
radiation dose delivered to tumors. An analytical approach is used to calculate dose …

Critical parameters to translate gold nanoparticles as radiosensitizing agents into the clinic

K Moloudi, A Khani, M Najafi… - Wiley …, 2023 - Wiley Online Library
Radiotherapy is an inevitable choice for cancer treatment that is applied as combinatorial
therapy along with surgery and chemotherapy. Nevertheless, radiotherapy at high doses …

Gold nanoparticles in radiotherapy and recent progress in nanobrachytherapy

M Laprise‐Pelletier, T Simão… - Advanced healthcare …, 2018 - Wiley Online Library
Over the last few decades, gold nanoparticles (GNPs) have emerged as “radiosensitizers” in
oncology. Radiosensitizers are additives that can enhance the effects of radiation on …

Biological modeling of gold nanoparticle enhanced radiotherapy for proton therapy

Y Lin, SJ McMahon, H Paganetti… - Physics in Medicine & …, 2015 - iopscience.iop.org
Gold nanoparticles (GNPs) have shown potential as a radiosensitizer for radiation therapy
using photon beams. Recently, experimental studies have been carried out using proton …

Combination of nanotechnology with vascular targeting agents for effective cancer therapy

R Jahanban‐Esfahlan, K Seidi… - Journal of cellular …, 2018 - Wiley Online Library
As a young science, nanotechnology promptly integrated into the current oncology practice.
Accordingly, various nanostructure particles were developed to reduce drug toxicity and …

[HTML][HTML] Gold nanoparticles meet medical radionuclides

N Daems, C Michiels, S Lucas, S Baatout… - Nuclear Medicine and …, 2021 - Elsevier
Thanks to their unique optical and physicochemical properties, gold nanoparticles have
gained increased interest as radiosensitizing, photothermal therapy and optical imaging …