Objective Nosebleed, also known as epistaxis, is a common problem that occurs at some
point in at least 60% of people in the United States. While the majority of nosebleeds are …

Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu
syndrome, is an autosomal dominant disorder that causes abnormal blood vessel formation …

Description: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant
disease with an estimated prevalence of 1 in 5000 that is characterized by the presence of …

Abstract Background Rare diseases (RDs) affect a small number of people within a
population. About 5000 to 8000 distinct RDs have been identified, with an estimated 6% to …

Hereditary hemorrhagic telangiectasia (HHT), also known by the eponym Osler–Weber–
Rendu syndrome, is a group of related disorders inherited in an autosomal dominant fashion …

Background Worldwide approximately 7,000 rare diseases have been identified.
Accordingly, 4 million individuals live with a rare disease in Germany. The mean time to …

In this review, we discuss the role of transforming growth factor-beta (TGF-β) in the
development of pulmonary vascular disease (PVD), both pulmonary arteriovenous …

Background Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant
genetic disorder of aberrant blood vessel development characterised by arteriovenous …

Hereditary hemorrhagic telangiectasia (HHT), the second most common inherited bleeding
disorder, is associated with the development of malformed blood vessels. Abnormal blood …

ALK1 controls hepatic vessel formation, angiodiversity, and... : Hepatology ALK1 controls
hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic …