Autoimmune diseases commonly affect various systems, but their etiology and pathogenesis
remain unclear. Currently, increasing research has highlighted the role of ferroptosis in …

Sarcopenia is a systemic disease with progressive and generalized skeletal muscle
dysfunction defined by age-related low muscle mass, high content of muscle slow fibers, and …

Plasma membrane integrity is essential for cellular homeostasis. In vivo, cells experience
plasma membrane damage from a multitude of stressors in the extra-and intra-cellular …

Ferroptosis is characterized by the accumulation of iron and lipid peroxidation products,
which regulates physiological and pathological processes in numerous organs and tissues …

In the broad field of inflammation, skeletal muscle is a tissue that is understudied. Yet it
represents about 40% of body mass in non-obese individuals and is therefore of …

Systemic autoimmune diseases are complex conditions characterized by an immune system
dysregulation and an aberrant activation against self-antigens, leading to tissue and organ …

Ferroptosis, a novel type of regulated cell death mediated by iron-dependent lipid oxidation,
was discovered a decade ago. Significant progress has been made in our knowledge of …

Plasma membrane injury can cause lethal influx of calcium, but cells survive by mounting a
polarized repair response targeted to the wound site. Mitochondrial signaling within seconds …

Systemic sclerosis (SSc) is a heterogeneous multisystem autoimmune disease whereby its
main pathological drivers of disability and damage are vascular injury, inflammatory cell …

Idiopathic inflammatory myopathies (IIM) and systemic lupus erythematosus (SLE) are
inflammatory connective tissue diseases (CTDs) with common features of arthritis, muscle …