Antimalarial drugs are key tools for the control and elimination of malaria. Recent decreases
in the global malaria burden are likely due, in part, to the deployment of artemisinin-based …

Piperazine is one of the most sought heterocyclics for the development of new drug
candidates. This ring can be traced in a number of well established, commercially available …

To limit the spread and impact of anti-malarial drug resistance and react accordingly,
surveillance systems able to detect and track in real-time its emergence and spread need to …

Abstract Context The Democratic Republic of Congo (DRC), one of the most malaria-
affected countries worldwide, is a potential hub for global drug-resistant malaria. This study …

ABSTRACT A major challenge to global malaria control and elimination is early detection
and containment of emerging drug resistance. Next-generation sequencing (NGS) methods …

Antimalarial drug resistance is a major constraint for malaria control and elimination efforts.
Artemisinin-based combination therapy is now the mainstay for malaria treatment. However …

ABSTRACT A key drawback to monitoring the emergence and spread of antimalarial drug
resistance in sub-Saharan Africa is early detection and containment. Next-generation …

The effectiveness of artemisinin-based combination therapies (ACTs) depends not only on
that of artemisinin but also on that of partner molecules. This study aims to evaluate the …

Intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-
SP) is used to prevent malaria and associated unfavorable maternal and foetal outcomes in …

The increased insecticides resistance by vectors and the ecological harm imposed by
insecticides to beneficial organisms drawback mosquitoes chemical control efforts …