MAGIC populations in crops: current status and future prospects

BE Huang, KL Verbyla, AP Verbyla… - Theoretical and Applied …, 2015 - Springer
Key message MAGIC populations present novel challenges and opportunities in crops due
to their complex pedigree structure. They offer great potential both for dissecting genomic …

Genome-wide association studies in mice

J Flint, E Eskin - Nature Reviews Genetics, 2012 - nature.com
Genome-wide association studies (GWASs) have transformed the field of human genetics
and have led to the discovery of hundreds of genes that are implicated in human disease …

An efficient multi-locus mixed-model approach for genome-wide association studies in structured populations

V Segura, BJ Vilhjálmsson, A Platt, A Korte, Ü Seren… - Nature …, 2012 - nature.com
Population structure causes genome-wide linkage disequilibrium between unlinked loci,
leading to statistical confounding in genome-wide association studies. Mixed models have …

Genome-wide association study of leaf architecture in the maize nested association mapping population

F Tian, PJ Bradbury, PJ Brown, H Hung, Q Sun… - Nature …, 2011 - nature.com
US maize yield has increased eight-fold in the past 80 years, with half of the gain attributed
to selection by breeders. During this time, changes in maize leaf angle and size have altered …

Stability selection

N Meinshausen, P Bühlmann - Journal of the Royal Statistical …, 2010 - academic.oup.com
Estimation of structure, such as in variable selection, graphical modelling or cluster analysis,
is notoriously difficult, especially for high dimensional data. We introduce stability selection …

The genetic architecture of maize height

JA Peiffer, MC Romay, MA Gore, SA Flint-Garcia… - Genetics, 2014 - academic.oup.com
Height is one of the most heritable and easily measured traits in maize (Zea mays L.). Given
a pedigree or estimates of the genomic identity-by-state among related plants, height is also …

Genome-wide association study of quantitative resistance to southern leaf blight in the maize nested association mapping population

KL Kump, PJ Bradbury, RJ Wisser, ES Buckler… - Nature …, 2011 - nature.com
Nested association mapping (NAM) offers power to resolve complex, quantitative traits to
their causal loci. The maize NAM population, consisting of 5,000 recombinant inbred lines …

A Multiparent Advanced Generation Inter-Cross to Fine-Map Quantitative Traits in Arabidopsis thaliana

PX Kover, W Valdar, J Trakalo, N Scarcelli… - PLoS …, 2009 - journals.plos.org
Identifying natural allelic variation that underlies quantitative trait variation remains a
fundamental problem in genetics. Most studies have employed either simple synthetic …

ZmCCT and the genetic basis of day-length adaptation underlying the postdomestication spread of maize

HY Hung, LM Shannon, F Tian… - Proceedings of the …, 2012 - National Acad Sciences
Teosinte, the progenitor of maize, is restricted to tropical environments in Mexico and
Central America. The pre-Columbian spread of maize from its center of origin in tropical …

Genetic architecture of maize kernel composition in the nested association mapping and inbred association panels

JP Cook, MD McMullen, JB Holland, F Tian… - Plant …, 2012 - academic.oup.com
The maize (Zea mays) kernel plays a critical role in feeding humans and livestock around
the world and in a wide array of industrial applications. An understanding of the regulation of …