Epstein–Barr virus infection

JI Cohen - New England journal of medicine, 2000 - Mass Medical Soc
The Epstein–Barr virus (EBV) was discovered 36 years ago by electron microscopy of cells
cultured from Burkitt's lymphoma tissue by Epstein, Achong, and Barr. 1 Four years later, in …

Cellular responses to viral infection in humans: lessons from Epstein-Barr virus

AD Hislop, GS Taylor, D Sauce… - Annu. Rev. Immunol …, 2007 - annualreviews.org
Epstein-Barr virus (EBV) provides a useful model to study cellular immunity to a genetically
stable, persistent human virus. Different sets of proteins expressed during EBV's lytic and …

Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients

HE Heslop, KS Slobod, MA Pule… - Blood, The Journal …, 2010 - ashpublications.org
T-cell immunotherapy that takes advantage of Epstein-Barr virus (EBV)–stimulated immunity
has the potential to fill an important niche in targeted therapy for EBV-related cancers. To …

Adoptive T cell therapy for cancer in the clinic

CH June - The Journal of clinical investigation, 2007 - Am Soc Clin Investig
The transfusion of lymphocytes, referred to as adoptive T cell therapy, is being tested for the
treatment of cancer and chronic infections. Adoptive T cell therapy has the potential to …

Adoptive-cell-transfer therapy for the treatment of patients with cancer

ME Dudley, SA Rosenberg - Nature Reviews Cancer, 2003 - nature.com
Adoptive immunotherapy—the isolation of antigen-specific cells, their ex vivo expansion and
activation, and subsequent autologous administration—is a promising approach to inducing …

T-cell therapy in the treatment of post-transplant lymphoproliferative disease

CM Bollard, CM Rooney, HE Heslop - Nature reviews Clinical oncology, 2012 - nature.com
Post-transplant lymphoproliferative diseases (PTLD) associated with Epstein-Barr virus
(EBV) infection often develop after organ and haematopoietic stem-cell transplantation …

Comparison of immune reconstitution after unrelated and related T-cell–depleted bone marrow transplantation: effect of patient age and donor leukocyte infusions

TN Small, EB Papadopoulos, F Boulad… - Blood, The Journal …, 1999 - ashpublications.org
Unrelated bone marrow transplantation (BMT) is often complicated by fatal opportunistic
infections. To evaluate features unique to immune reconstitution after unrelated BMT, the …

Post-transplant lymphoproliferative disorders

S Gottschalk, CM Rooney, HE Heslop - Annu. Rev. Med., 2005 - annualreviews.org
Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening complication after
hematopoietic stem cell or solid organ transplantation. The majority of PTLD is of B-cell …

How I treat EBV lymphoproliferation

HE Heslop - Blood, The Journal of the American Society of …, 2009 - ashpublications.org
Abstract Epstein-Barr virus (EBV)–associated B-cell lymphoproliferation is a life-threatening
complication after hematopoietic stem cell or solid organ transplantation resulting from …

Prevention of Epstein-Barr virus–lymphoproliferative disease by molecular monitoring and preemptive rituximab in high-risk patients after allogeneic stem cell …

JWJ van Esser, HGM Niesters… - Blood, The Journal …, 2002 - ashpublications.org
Recipients of a partially T-cell–depleted (TCD) allogeneic stem cell transplantation (allo-
SCT) developing reactivation of Epstein-Barr virus (EBV) with quantified viral DNA levels …