Current perspectives in human T-cell leukemia virus type 1 infection and its associated diseases

M Miura, T Naito, M Saito - Frontiers in Medicine, 2022 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) is a replication-competent human retrovirus
associated with two distinct types of diseases: a malignancy of mature CD4+ T cells called …

miRNAs: biogenesis, origin and evolution, functions on virus-host interaction

Y Zhuo, G Gao, J Shi, X Zhou, X Wang - Cellular Physiology and …, 2013 - karger.com
MicroRNAs (miRNAs) are small endogenous non-coding functional RNAs. They can play
vital roles in post-transcriptional regulating mRNAs transcripts in nearly all biological …

A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptor

P Reichenbach, GMP Giordano Attianese… - Nature Biomedical …, 2023 - nature.com
Vectors that facilitate the engineering of T cells that can better harness endogenous
immunity and overcome suppressive barriers in the tumour microenvironment would help …

miR-28-3p is a cellular restriction factor that inhibits human T cell leukemia virus, type 1 (HTLV-1) replication and virus infection

XT Bai, C Nicot - Journal of Biological Chemistry, 2015 - ASBMB
Human T cell leukemia virus, type 1 (HTLV-1) replication and spread are controlled by
different viral and cellular factors. Although several anti-HIV cellular microRNAs have been …

[HTML][HTML] STAT1: A novel target of miR-150 and miR-223 is involved in the proliferation of HTLV-I–transformed and ATL cells

R Moles, M Bellon, C Nicot - Neoplasia, 2015 - Elsevier
We have previously reported on the deregulation of cellular microRNAs involved in
hematopoiesis and inflammation in human T-cell lymphotropic virus type 1 (HTLV-I) …

NF-κB and MicroRNA deregulation mediated by HTLV-1 tax and HBZ

S Fochi, V Ciminale, E Trabetti, U Bertazzoni… - Pathogens, 2019 - mdpi.com
The risk of developing adult T-cell leukemia/lymphoma (ATLL) in individuals infected with
human T-cell lymphotropic virus 1 (HTLV-1) is about 3–5%. The mechanisms by which the …

HTLV-1/-2 and HIV-1 co-infections: retroviral interference on host immune status

E Pilotti, MV Bianchi, A De Maria, F Bozzano… - Frontiers in …, 2013 - frontiersin.org
The human retroviruses HIV-1 and HTLV-1/HTLV-2 share similar routes of transmission but
cause significantly different diseases. In this review we have outlined the immune mediated …

WRN-targeted therapy using inhibitors NSC 19630 and NSC 617145 induce apoptosis in HTLV-1-transformed adult T-cell leukemia cells

R Moles, XT Bai, H Chaib-Mezrag, C Nicot - Journal of Hematology & …, 2016 - Springer
Background Human T-cell leukemia virus type 1 (HTLV-1) infection is associated with adult
T-cell leukemia/lymphoma (ATLL), a lymphoproliferative malignancy with a dismal prognosis …

Oncogenic microRNAs in the genesis of leukemia and lymphoma

Y Pan, M Meng, G Zhang, H Han… - Current pharmaceutical …, 2014 - ingentaconnect.com
Emerging evidence has shown that microRNAs (miRNAs) can act as oncogenes in the
initiation and progression of leukemia and lymphoma. Aberrant expression of oncogenic …

[HTML][HTML] Impaired expression of DICER and some microRNAs in HBZ expressing cells from acute adult T-cell leukemia patients

H Gazon, G Belrose, M Terol, JC Meniane… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Global dysregulation of microRNAs (miRNAs), a class of non-coding RNAs that regulate
genes expression, is a common feature of human tumors. Profiling of cellular miRNAs on …