Quinoline (1-azanaphthalene) is a heterocyclic aromatic nitrogen compound characterized
by a double-ring structure that contains a benzene ring fused to pyridine at two adjacent …

Introduction: The concept of privileged structures is well known and is often used in the
process of drug design and development. Although its assumptions are not clear, its overall …

Cancer is one of the leading causes of death globally, around 10 million deaths are reported
every year due to cancer. Some clinically approved anticancer drugs play a riveting role in …

Podstawowym celem mojej pracy było poszukiwanie nowych heteroaromatycznych
chelatorów żelaza, obejmujących funkcję tiosemikarbazonu. Badania obejmowały …

The increasing demand for new bioactive compounds to combat the evolution of multi-drug
resistance (MDR) requires research on microorganisms in different environments in order to …

Infective diseases have become health threat of a global proportion due to appearance and
spread of microorganisms resistant to majority of therapeutics currently used for their …

Hydroxyquinoline (8–HQ) is known for its strong coordination and chelation behaviours.
Because of this, 8–HQ and its derivatives manifest exceptionally high potential for corrosion …

Quinoline is one of the most widely investigated scaffolds by synthetic chemists because of
its medicinal importance. A wide range of metal-catalyzed, metal-free, multi-step or domino …

Copper is a ubiquitous element in the environment as well as living organisms, with its redox
capabilities and complexation potential making it indispensable for many cellular functions …

Here in, we report the design, synthesis and in vitro anticancer activity of a novel series of 24
quinoline analogues of substituted amide and sulphonamide derivatives. The anticancer …