Interplay between Candida albicans and the mammalian innate host defense

SC Cheng, LAB Joosten, BJ Kullberg… - Infection and …, 2012 - Am Soc Microbiol
Candida albicans is both the most common fungal commensal microorganism in healthy
individuals and the major fungal pathogen causing high mortality in at-risk populations …

Perspectives for clinical use of engineered human host defense antimicrobial peptides

ME Pachón-Ibáñez, Y Smani, J Pachon… - FEMS microbiology …, 2017 - academic.oup.com
Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …

An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans

AG Hise, J Tomalka, S Ganesan, K Patel, BA Hall… - Cell host & …, 2009 - cell.com
Candida albicans is an opportunistic fungal pathogen causing life-threatening mucosal and
systemic infections in immunocompromised humans. Using a murine model of mucosal …

Activity of phenolic compounds from plant origin against Candida species

N Martins, L Barros, M Henriques, S Silva… - Industrial Crops and …, 2015 - Elsevier
Candida albicans and other Candida species have been highly associated with several
opportunistic fungal infections. Their ability to develop host infections is incited by different …

Candidal onychomycosis: a mini-review

J Jayatilake, WM Tilakaratne, GJ Panagoda - Mycopathologia, 2009 - Springer
Onychomycosis is a common fungal infection affecting nails. The primary cause for
onychomycosis is dermatophytes, while Candida species have emerged as second-line …

Interplay between Candida albicans and the antimicrobial peptide armory

M Swidergall, JF Ernst - Eukaryotic cell, 2014 - Am Soc Microbiol
Antimicrobial peptides (AMPs) are key elements of innate immunity, which can directly kill
multiple bacterial, viral, and fungal pathogens. The medically important fungus Candida …

Architectural analysis, viability assessment and growth kinetics of Candida albicans and Candida glabrata biofilms

CJ Seneviratne, WJ Silva, LJ Jin… - Archives of oral …, 2009 - Elsevier
The human fungal pathogen Candida is able to form biofilms in almost all the medical
devices in current use. Indeed, biofilm formation is a major virulence attribute of …

Role of β-defensins in oral epithelial health and disease

Y Abiko, M Saitoh, M Nishimura, M Yamazaki… - Medical molecular …, 2007 - Springer
The oral epithelium functions as a mechanical and protective barrier to resist bacterial
infection. β-Defensins are a group of antimicrobial peptides mainly produced by epithelial …

Cell Density and Cell Aging as Factors Modulating Antifungal Resistance of Candida albicans Biofilms

CJ Seneviratne, LJ Jin, YH Samaranayake… - Antimicrobial agents …, 2008 - Am Soc Microbiol
Biofilm formation is a major virulence attribute of Candida pathogenicity which contributes to
higher antifungal resistance. We investigated the roles of cell density and cellular aging on …

[HTML][HTML] Barrier function, epidermal differentiation, and human β-defensin 2 expression in Tinea Corporis

JM Jensen, S Pfeiffer, T Akaki, JM Schröder… - Journal of investigative …, 2007 - Elsevier
Tinea corporis is a superficial mycotic infection resulting in substantial epidermal changes.
We determined skin barrier function, epidermal differentiation, and human-β-defensin 2 …