Antioxidant for neurological diseases and neurotrauma and bioengineering approaches

N Rizwana, V Agarwal, M Nune - Antioxidants, 2021 - mdpi.com
Antioxidants are a class of molecules with an innate affinity to neutralize reactive oxygen
species (ROS), which are known to cause oxidative stress. Oxidative stress has been …

Vitexin alleviates high-fat diet induced brain oxidative stress and inflammation via anti-oxidant, anti-inflammatory and gut microbiota modulating properties

S Li, T Liang, Y Zhang, K Huang, S Yang, H Lv… - Free Radical Biology …, 2021 - Elsevier
Vitexin, a millet-derived flavonoid, has been reported to have many biological activities. The
present study investigated the function of vitexin in neural oxidative stress and neuro …

Vitamin E exerts neuroprotective effects in pentylenetetrazole kindling epilepsy via suppression of ferroptosis

X Zhang, S Wu, C Guo, K Guo, Z Hu, J Peng… - Neurochemical …, 2022 - Springer
Epilepsy is one of the most common chronic neurological diseases. There is increasing
evidence for ferroptosis playing an important role in the occurrence and development of …

Relaxing the “second brain”: nutrients and bioactive compounds as a therapeutic and preventive strategy to alleviate oxidative stress in the enteric nervous system

PP Almeida, AL Tavares-Gomes… - Nutrition …, 2022 - academic.oup.com
The enteric nervous system (ENS) regulates several functional and immunological
processes in the gastrointestinal tract. However, some diseases can disrupt the ENS …

Effect of fresh pomegranate juice on the level of melatonin, insulin, and fasting serum glucose in healthy individuals and people with impaired fasting glucose

SA Banihani, RA Fashtaky, SM Makahleh… - Food science & …, 2020 - Wiley Online Library
Pomegranate juice (PGJ) is rich in unique bioactive compounds that can be used in the
management of various diseases/disorders such as cancer, heart disease, Alzheimer …

[PDF][PDF] Evaluation of ivermectin and vitamin E based combination with antiseizure rufinamide drug for mitigation of pentylenetetrazole-induced kindling, behavioral …

A Sabir, S Tehreem, M Farooq, W Ashraf… - Journal of Physiology …, 2024 - researchgate.net
Pentylenetetrazole-(PTZ)-induced kindling is a broadly used experimental model to evaluate
the impact of antiseizure drugs and their novel combination on seizure progression. The …

Neuroprotective and Cardiometabolic Role of Vitamin E: Alleviating Neuroinflammation and Metabolic Disturbance Induced by AlCl3 in Rat Models

K Jabeen, K Rehman, MSH Akash, A Nadeem, TM Mir - Biomedicines, 2023 - mdpi.com
Cardiovascular diseases (CVDs) and neurodegenerative disorders, such as diabetes
mellitus and Alzheimer's disease, share a common pathophysiological link involving insulin …

The ferroptosis inducer RSL3 triggers interictal epileptiform activity in mice cortical neurons

M Giustizieri, S Petrillo, J D'Amico, C Torda… - Frontiers in Cellular …, 2023 - frontiersin.org
Epilepsy is a neurological disorder characterized by recurrent seizures, which result from
excessive, synchronous discharges of neurons in different brain areas. In about 30% of …

Pentoxifylline protects memory performance in streptozotocin-induced diabetic rats

M Muhsen, KH Alzoubi, OF Khabour, N Mhaidat… - Brain Research, 2025 - Elsevier
Diabetes, characterized by elevated blood glucose levels and associated organ damage, is
reportedly correlated with a decline in cognitive functions with a potential involvement of …

Diet-derived circulating antioxidants and risk of epilepsy: A study combining metabolomics and mendelian randomization

Z Liang, Y Lou, Z Zheng, Q Guo, S Liu - Heliyon, 2024 - cell.com
Background Previous studies offer inconclusive results on the association between diet-
derived circulating antioxidants and epilepsy. Objective This study aims to assess oxidative …