Hypohydration, defined as a state of low body water, increases thirst sensations, arginine
vasopressin release, and elicits renin–angiotensin–aldosterone system activation to …

Shock is deadly and unpredictable if it is not recognized and treated in early stages of
hemorrhage. Unfortunately, measurements of standard vital signs that are displayed on …

The ability to quickly diagnose hemorrhagic shock is critical for favorable patient outcomes.
Therefore, it is important to understand the time course and involvement of the various …

The purpose of this study was to compare hemodynamic and blood analyte responses to
reduced central venous pressure (CVP) and pulse pressure (PP) elicited during graded …

EditordIn clinically significant hypovolaemia, reduced venous return and cardiac filling
diminish stroke volume (SV) and compensatory adrenergic tone raises systemic vascular …

Trauma is the leading cause of death during the first four decades of life in the developed
countries. Its haemodynamic response underpins the patient's initial ability to survive, and …

As the leading cause of trauma-related mortality, blood loss due to hemorrhage is
notoriously difficult to triage and manage. To enable timely and appropriate care for patients …

Haemodynamic oscillations occurring at frequencies below the rate of respiration have been
observed experimentally for more than a century. Much of the research regarding these …

Vital signs historically served as the primary method to triage patients and resources for
trauma and emergency care, but have failed to provide clinically-meaningful predictive …

The microvasculature plays a central role in the pathophysiology of hemorrhagic shock and
is also involved in arguably all therapeutic attempts to reverse or minimize the adverse …