Opportunities and challenges for co-delivery nanomedicines based on combination of phytochemicals with chemotherapeutic drugs in cancer treatment

Q Gao, J Feng, W Liu, C Wen, Y Wu, Q Liao… - Advanced drug delivery …, 2022 - Elsevier
The therapeutic limitations such as insufficient efficacy, drug resistance, metastasis, and
undesirable side effects are frequently caused by the long duration monotherapy based on …

[HTML][HTML] Colon cancer and colorectal cancer: Prevention and treatment by potential natural products

MR Islam, S Akash, MM Rahman, FT Nowrin… - Chemico-biological …, 2022 - Elsevier
Colon cancer affects both men and women and is the world's second most significant cause
of cancer-related mortality. Colon cancer death rates have risen worldwide due to the …

Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets

P Asgharian, AP Tazekand, K Hosseini… - Cancer cell …, 2022 - Springer
Over the past few years, the cancer-related disease has had a high mortality rate and
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …

The role of the gut microbiome in colorectal cancer development and therapy response

L Sánchez-Alcoholado, B Ramos-Molina, A Otero… - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

Quercetin and cancer: new insights into its therapeutic effects on ovarian cancer cells

A Vafadar, Z Shabaninejad, A Movahedpour, F Fallahi… - Cell & bioscience, 2020 - Springer
Ovarian cancer is known as a serious malignancy that affects women's reproductive tract
and can considerably threat their health. A wide range of molecular mechanisms and …

Adverse effects of cancer chemotherapy: Anything new to improve tolerance and reduce sequelae?

K Nurgali, RT Jagoe, R Abalo - Frontiers in pharmacology, 2018 - frontiersin.org
The side-effects and long-term sequelae of anti-cancer chemotherapy remain a major
source of concern for both patients and clinicians despite the improved efficacy and …

[HTML][HTML] Apigenin enhances apoptosis induction by 5-fluorouracil through regulation of thymidylate synthase in colorectal cancer cells

C Yang, J Song, S Hwang, J Choi, G Song, W Lim - Redox biology, 2021 - Elsevier
Although effective drugs have been developed, including 5-fluorouracil (5-FU), advanced
colorectal cancer (CRC) shows low therapeutic sensitivity resulting from the development of …

Quercetin: a functional dietary flavonoid with potential chemo‐preventive properties in colorectal cancer

SG Darband, M Kaviani, B Yousefi… - Journal of Cellular …, 2018 - Wiley Online Library
Recently, an intense attention has been paid to the application of natural compounds as a
novel therapeutic strategy for cancer treatment. Quercetin, a natural flavonol present in many …

Targets involved in the anti-cancer activity of quercetin in breast, colorectal and liver neoplasms

A Maugeri, A Calderaro, GT Patanè, M Navarra… - International Journal of …, 2023 - mdpi.com
Phytochemicals have long been effective partners in the fight against several diseases,
including cancer. Among these, flavonoids are valuable allies for both cancer prevention …

Reversal of multidrug resistance in cancer by multi-functional flavonoids

Q Ye, K Liu, Q Shen, Q Li, J Hao, F Han… - Frontiers in …, 2019 - frontiersin.org
Multidrug resistance (MDR) resulting from different defensive mechanisms in cancer is one
of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have …