Cyclopropanes are key features in many preclinical, clinical, and commercial drugs, as well
as natural products. The most prolific technique for their synthesis is the metal-catalyzed …

Herein, we describe a practical protocol for the removal of alcohol functional groups through
reductive cleavage of their benzoate ester analogs. This transformation requires a strong …

Cyclopropane skeletons play a prominent role in the development of organic synthesis and
pharmaceutical chemistry. Herein, we report the design and synthesis of a stable …

Cyclopropanes are among the most important structural units in natural products,
pharmaceuticals, and agrochemicals. Herein, we report a manganese-catalyzed …

Transition metal‐catalyzed site‐and stereoselective C− H activation of strained (hetero)
cycloalkanes remains a formidable challenge. We herein report a carbamate‐directed …

We describe the first catalytic generation of Fischer-type acyloxy Rh (II)-carbenes from
carboxylic acids and Rh (II)-carbynoids. This novel class of transient donor/acceptor Rh (II) …

Ketones are ubiquitous in organic synthesis. However, the general method to convert widely
available carboxylic acids, unactivated esters, and amides into ketones remains elusive …

Transition metal‐catalyzed carbene transfer reactions have a century‐old history in organic
chemistry and are a primary method for the synthesis of cyclopropanes. Much of the work in …

Cyclopropanes are not only privileged motifs in many natural products, agrochemicals, and
pharmaceuticals, but also highly versatile intermediates in synthetic chemistry. As such …

Development of robust d 3-methylthiolating reagents represents an attractive synthetic
method to access deuterated molecules in the field of drug discovery. Here, we report a …