The evolution of polystyrene as a cell culture material

MJ Lerman, J Lembong, S Muramoto… - … Engineering Part B …, 2018 - liebertpub.com
Polystyrene (PS) has brought in vitro cell culture from its humble beginnings to the modern
era, propelling dozens of research fields along the way. This review discusses the …

Integrating biomaterials and food biopolymers for cultured meat production

S Ng, M Kurisawa - Acta Biomaterialia, 2021 - Elsevier
Cultured meat has recently achieved mainstream prominence due to the emergence of
societal and industrial interest. In contrast to animal-based production of traditional meat, the …

Mesenchymal stromal cell therapy: progress in manufacturing and assessments of potency

KP Robb, JC Fitzgerald, F Barry, S Viswanathan - Cytotherapy, 2019 - Elsevier
Mesenchymal stromal cell (MSC) therapies have been pursued for a broad spectrum of
indications but mixed reports on clinical efficacy have given rise to some degree of …

Influence of microenvironment on mesenchymal stem cell therapeutic potency: from planar culture to microcarriers

AC Tsai, R Jeske, X Chen, X Yuan, Y Li - Frontiers in bioengineering …, 2020 - frontiersin.org
Human mesenchymal stem cells (hMSCs) are a promising candidate in cell therapy as they
exhibit multilineage differentiation, homing to the site of injury, and secretion of trophic …

Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds

PS Couto, MC Rotondi, A Bersenev, CJ Hewitt… - Biotechnology …, 2020 - Elsevier
Human mesenchymal stem/stromal cells (hMSCs) present a key therapeutic cellular
intervention for use in cell and gene therapy (CGT) applications due to their …

[HTML][HTML] Recent advances in bioreactors for cell-based therapies

M Stephenson, W Grayson - F1000Research, 2018 - ncbi.nlm.nih.gov
Bioreactors have become indispensable tools in the cell-based therapy industry. Various
forms of bioreactors are used to maintain well-controlled microenvironments to regulate cell …

[HTML][HTML] Human mesenchymal stem cell therapy for cartilage repair: review on isolation, expansion, and constructs

ATL Lam, S Reuveny, SKW Oh - Stem Cell Research, 2020 - Elsevier
Articular cartilage defects are one of the major challenges in orthopedic and trauma surgery.
However, the poor ability of cartilage to self-repair has motivated efforts to engineer …

Bioengineering outlook on cultivated meat production

I Pajčin, T Knežić, I Savic Azoulay, V Vlajkov… - Micromachines, 2022 - mdpi.com
Cultured meat (also referred to as cultivated meat or cell-based meat)—CM—is fabricated
through the process of cellular agriculture (CA), which entails application of bioengineering …

Scalable microcarrier-based manufacturing of mesenchymal stem/stromal cells

AM de Soure, A Fernandes-Platzgummer… - Journal of …, 2016 - Elsevier
Due to their unique features, mesenchymal stem/stromal cells (MSC) have been exploited in
clinical settings as therapeutic candidates for the treatment of a variety of diseases …

The applications of heparin in vascular tissue engineering

S Aslani, M Kabiri, S HosseinZadeh… - Microvascular …, 2020 - Elsevier
Cardiovascular diseases, among all diseases, are taking the most victims worldwide.
Coronary artery occlusion, takes responsibility of about 30% of the yearly global deaths in …