Nanogels: Synthesis, properties, and recent biomedical applications

QY Duan, YX Zhu, HR Jia, SH Wang, FG Wu - Progress in Materials …, 2023 - Elsevier
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …

Pharmacological activities and mechanisms of hirudin and its derivatives-a review

C Junren, X Xiaofang, Z Huiqiong, L Gangmin… - Frontiers in …, 2021 - frontiersin.org
Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also
known as “Shuizhi” in traditional Chinese medicine), is the strongest natural specific inhibitor …

Theory, observation, and ultrafast response of the hybrid anapole regime in light scattering

A Canós Valero, EA Gurvitz… - Laser & Photonics …, 2021 - Wiley Online Library
Modern nanophotonics has witnessed the rise of “electric anapoles”(EDAs), destructive
interferences of electric and toroidal electric dipoles, actively exploited to resonantly …

Platelet-covered nanocarriers for targeted delivery of hirudin to eliminate thrombotic complication in tumor therapy

K Zhang, Z Ma, S Li, W Zhang, MF Foda, Y Zhao… - ACS …, 2022 - ACS Publications
Most patients are at high risk of thrombosis during cancer treatment. However, the major
discrepancy in the therapeutic mechanisms and microenvironment between tumors and …

Minimalist nanocomplex with dual regulation of endothelial function and inflammation for targeted therapy of inflammatory vascular diseases

S Wang, Y Wang, X Lai, J Sun, M Hu, M Chen, C Li… - ACS …, 2023 - ACS Publications
Vascular disorders, characterized by vascular endothelial dysfunction combined with
inflammation, are correlated with numerous fatal diseases, such as coronavirus disease-19 …

Advanced drug delivery system against ischemic stroke

S Zhang, Y Zhou, R Li, Z Chen, X Fan - Journal of Controlled Release, 2022 - Elsevier
Ischemic stroke is a vascular central nervous system (CNS) disease that leads a disability
and death. Thrombolysis and neuroprotection are the primary treatment strategies of …

Cell–drug conjugates

Y Wang, J Shi, M Xin, AR Kahkoska, J Wang… - Nature Biomedical …, 2024 - nature.com
By combining living cells with therapeutics, cell–drug conjugates can potentiate the
functions of both components, particularly for applications in drug delivery and therapy. The …

Biomimetic Nanoplatelets to Target Delivery Hirudin for Site‐Specific Photothermal/Photodynamic Thrombolysis and Preventing Venous Thrombus Formation

S Li, K Zhang, Z Ma, W Zhang, Z Song, W Wang, H Han - Small, 2022 - Wiley Online Library
Due to the high recurrence rate and mortality of venous thrombosis, there is an urgent need
for research on antithrombotic strategies. Because of the short half‐life, poor targeting …

Recent progress of optoelectronic and all‐optical neuromorphic devices: a comprehensive review of device structures, materials, and applications

S Song, J Kim, SM Kwon, JW Jo… - Advanced Intelligent …, 2021 - Wiley Online Library
Conventional von Neumann–based computing systems have inherent limitations such as
high hardware complexity, relatively inferior energy efficiency, and low bandwidth. As an …

An intelligent DNA nanodevice for precision thrombolysis

J Yin, S Wang, J Wang, Y Zhang, C Fan, J Chao… - Nature Materials, 2024 - nature.com
Thrombosis is a leading global cause of death, in part due to the low efficacy of thrombolytic
therapy. Here, we describe a method for precise delivery and accurate dosing of tissue …