Chronic obstructive pulmonary disease (COPD) is a deadly and highly morbid disease.
Susceptibility to and heterogeneity of COPD are incompletely explained by environmental …

Although chronic obstructive pulmonary disease (COPD) risk is strongly influenced by
cigarette smoking, genetic factors are also important determinants of COPD. In addition to …

The factors mediating fatal SARS-CoV-2 infections are poorly understood. Here, we show
that cigarette smoke causes a dose-dependent upregulation of angiotensin converting …

Chronic obstructive pulmonary disease (COPD), the third leading cause of death worldwide,
is highly heritable. While COPD is clinically defined by applying thresholds to summary …

Extravasation of monocytes into tissue and to the site of injury is a fundamental
immunological process, which requires rapid responses via post translational modifications …

In this study, we integrate the outcomes of co-expression network analysis with the human
interactome network to predict novel putative disease genes and modules. We first apply the …

Lung squamous cell carcinoma (LUSC) is often diagnosed at the advanced stage with poor
prognosis. The mechanisms of its pathogenesis and prognosis require urgent elucidation …

Chronic obstructive pulmonary disease is a complex condition with multiple etiologies,
including inflammation. We identified a novel long noncoding RNA (lncRNA), interleukin 6 …

Disturbances in mitochondrial structure and function in lung epithelial cells have been
implicated in the pathogenesis of various lung diseases, including chronic obstructive …

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality
worldwide. COPD heterogeneity has hampered progress in developing pharmacotherapies …