Abstract CD133 (prominin-1), a pentaspan membrane glycoprotein, is one of the most well-
characterized biomarkers used for the isolation of cancer stem cells (CSCs). The presence …

Astrocytes are the most prevalent glial cells in the brain. Historically considered as “merely
supporting” neurons, recent research has shown that astrocytes actively participate in a …

Early disruptions to neurodevelopment are highly relevant to understanding both psychiatric
risk and underlying pathophysiology that can be targeted by new treatments. Much …

Polycomb group (PcG) proteins are epigenetic modifiers involved in controlling gene
repression. Organized within multiprotein complexes, they regulate developmental genes in …

During neocortical development, neural precursor cells (NPCs, or neural stem cells)
produce neurons first and astrocytes later. Although the timing of the fate switch from …

The temporally and spatially restricted nature of the differentiation capacity of cells in the
neural lineage has been studied extensively in recent years. Epigenetic control of …

RNA‐binding proteins (RBPs) mediate the localization, stability, and translation of the target
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …

Cortical intermediate progenitors (IPs) comprise a secondary neuronal progenitor pool that
arises from radial glia (RG). IPs are essential for generating the correct number of cortical …

Stem cells are captivating because they have the potential to make multiple cell types yet
maintain their undifferentiated state. Recent studies of Drosophila and mammalian neural …

The capacity of neurons to develop a long axon and multiple dendrites defines neuron
connectivity in the CNS. The highly conserved microRNA-9 (miR-9) is expressed in both …