Probing and manipulating noncovalent interactions in functional polymeric systems

J Chen, Q Peng, X Peng, H Zhang, H Zeng - Chemical Reviews, 2022 - ACS Publications
Noncovalent interactions, which usually feature tunable strength, reversibility, and
environmental adaptability, have been recognized as driving forces in a variety of biological …

Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

[HTML][HTML] Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: From intrinsic physicochemical properties to external modification

H Mei, S Cai, D Huang, H Gao, J Cao, B He - Bioactive materials, 2022 - Elsevier
The considerable development of carrier-free nanodrugs has been achieved due to their
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …

Spatiotemporally programmable cascade hybridization of hairpin DNA in polymeric nanoframework for precise siRNA delivery

F Li, W Yu, J Zhang, Y Dong, X Ding, X Ruan… - Nature …, 2021 - nature.com
DNA nanostructures have been demonstrated as promising carriers for gene delivery. In the
carrier design, spatiotemporally programmable assembly of DNA under nanoconfinement is …

Tumor targeting strategies of smart fluorescent nanoparticles and their applications in cancer diagnosis and treatment

J He, C Li, L Ding, Y Huang, X Yin, J Zhang… - Advanced …, 2019 - Wiley Online Library
Advantages such as strong signal strength, resistance to photobleaching, tunable
fluorescence emissions, high sensitivity, and biocompatibility are the driving forces for the …

Precision-guided missile-like DNA nanostructure containing warhead and guidance control for aptamer-based targeted drug delivery into cancer cells in vitro and in …

C Ouyang, S Zhang, C Xue, X Yu, H Xu… - Journal of the …, 2020 - ACS Publications
It is crucial to deliver anticancer drugs to target cells with high precision and efficiency. While
nanomaterials have been shown to enhance the delivery efficiency once they reach the …

De novo design of phototheranostic sensitizers based on structure-inherent targeting for enhanced cancer ablation

M Li, S Long, Y Kang, L Guo, J Wang… - Journal of the …, 2018 - ACS Publications
Structure-inherent targeting (SIT) agents are of particular importance for clinical precision
medicine; however, there still exists a great lack of SIT phototheranostics for simultaneous …

Light‐induced self‐escape of spherical nucleic acid from endo/lysosome for efficient non‐cationic gene delivery

L Shi, W Wu, Y Duan, L Xu, Y Xu, L Hou… - Angewandte Chemie …, 2020 - Wiley Online Library
Developing non‐cationic gene carriers and achieving efficient endo/lysosome escape of
functional nucleic acids in cytosol are two major challenges faced by the field of gene …

DNA-inspired anti-freezing wet-adhesion and tough hydrogel for sweaty skin sensor

X Liu, Q Zhang, G Gao - Chemical Engineering Journal, 2020 - Elsevier
Epidermal sensors via self-adhesive hydrogels offer great promise for the motion detection,
health monitoring, and disease diagnosis. However, the self-adhesion of recent hydrogel …

Bioinspired nucleobase-driven nonswellable adhesive and tough gel with excellent underwater adhesion

X Liu, Q Zhang, L Duan, G Gao - ACS applied materials & …, 2019 - ACS Publications
Underwater adhesives have drawn much attention in the areas of industrial and biomedical
fields. However, it is still demanding to construct a tough underwater gel-based adhesive …