Endothelial cells are at the interface between circulating blood and tissues. This position
confers on them a crucial role in controlling oxygen and nutrient exchange and cellular …

Transforming growth factor β (TGF-β) superfamily signaling pathways are ubiquitous and
essential regulators of cellular processes including proliferation, differentiation, migration …

The major vascular disorders of the liver are listed in Table 2. Most of the vascular disorders
of the liver are rare, with the exception of portal vein thrombosis (PVT) in patients with …

Hereditary haemorrhagic telangiectasia, inherited as an autosomal dominant trait, affects
approximately 1 in 5000 people. The abnormal vascular structures in HHT result from …

The autosomal-dominant trait hereditary haemorrhagic telangiectasia (HHT) affects 1 in 5–
8000 people. Genes mutated in HHT (most commonly for endoglin or activin receptor-like …

Hereditary hemorrhagic telangiectasia (HHT) management is evolving because of the
emergence and development of antiangiogenic therapies to eliminate bleeding …

Pulmonary arteriovenous malformations (PAVMs) are abnormal vascular structures that
most often connect a pulmonary artery to a pulmonary vein, bypassing the normal …

Cerebral arteriovenous malformations (AVMs) entail a significant risk of intracerebral
hemorrhage owing to the direct shunting of arterial blood into the venous vasculature …

Hereditary hemorrhagic telangiectasia (HHT), also known by the eponym Osler–Weber–
Rendu syndrome, is a group of related disorders inherited in an autosomal dominant fashion …

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder
characterized by severe and recurrent nosebleeds, mucocutaneous telangiectases, and, in …