Breast cancer is a heterogeneous disease, with different subtypes having a distinct
biological, molecular, and clinical course. Assessments of standard clinical and pathological …

ABSTRACT Introduction: Formalin-fixed, paraffin-embedded (FFPE) tissue sample is a gold
mine of resources for molecular diagnosis and retrospective clinical studies. Although …

Alzheimer's disease (AD) is the most common cause of dementia, yet there is no cure or
diagnostics available prior to the onset of clinical symptoms. Extracellular vesicles (EVs) are …

Abstract Motivation: The NanoString nCounter Platform is a new and promising technology
for measuring nucleic acid abundances. It has several advantages over PCR-based …

Targeting EGFR is a validated approach in the treatment of squamous-cell cancers (SCCs),
although there are no established biomarkers for predicting response. We have identified a …

Body fluid identification is a key component in the forensic scientists' tool box and has been
carried out both at the crime scene and in the laboratory for many years. Historically …

The advanced medium-throughput NanoString nCounter technology has been increasingly
used for mRNA or miRNA differential expression (DE) studies due to its advantages …

Background: Metabolic disorder increases the risk of abdominal aortic aneurysm (AAA). NRs
(nuclear receptors) have been increasingly recognized as important regulators of cell …

Type I interferonopathies are characterized by an increase of circulating type I interferon
(IFN) concentration. Type I interferonopathies refer to rare Mendelian genetic disorders such …

Introduction: NanoString nCounter technology, a novel molecular assay, is gaining prevalent
use in clinical settings as it can overcome some common constraints that are associated with …