Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …

Cholangiocarcinoma (CCA) is a heterogeneous disease arising from a complex interaction
between host‐specific genetic background and multiple risk factors. Globally, CCA …

Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct
strictures and progressive liver disease. Inflammatory bowel disease is usually present and …

Background & Aims Primary sclerosing cholangitis (PSC) is an orphan hepatobiliary
disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of …

Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …

Cholangiocarcinomas are a heterogeneous group of malignancies arising from a number of
cells of origin along the biliary tree. Although most cases in Western countries are sporadic …

These guidelines on the management of primary sclerosing cholangitis (PSC) were
commissioned by the British Society of Gastroenterology liver section. The guideline writing …

Objective Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease often
leading to end-stage liver disease. Its pathogenesis remains largely unknown, although …