Rubin et al, 1, 2, 3 Emami et al, 4, 5 and Quantitative Analyses of Normal Tissue Effects in
the Clinic (QUANTEC) 6 provided estimates of dose, volume, and outcome data primarily for …

Dose constraints are essential for performing dosimetry, especially for intensity modulation
and for radiotherapy under stereotaxic conditions. We present the update of the …

Purpose This guideline provides updated evidence-based recommendations addressing
recent developments in the management of patients with brain metastases, including …

The use of stereotactic ablative radiotherapy (SABR) in the UK has expanded over the past
decade, in part as the result of several UK clinical trials and a recent NHS England …

Background Radiation necrosis (RN) secondary to stereotactic radiosurgery is a significant
cause of morbidity. The optimal management of corticosteroid-refractory brain RN remains …

Background Radiation-induced brain injury (RIBI) is the most serious complication of
radiotherapy in patients with head and neck tumors, which seriously affects the quality of life …

Brain metastases (BMs) represent the most frequent event during the course of Non-Small
Cell Lung Cancer (NSCLC) disease. Recent advancements in the diagnostic and …

Background: The safe use of radiotherapy (RT) requires compliance with dose/volume
constraints (DVCs) for organs at risk (OaRs). However, the available recommendations are …

Abstract Purpose Compared to CONV‐RT (with conventional dose rate), FLASH‐RT (with
ultra‐high dose rate) can provide biological dose sparing for organs‐at‐risk (OARs) via the …

Simple Summary Brain metastases are one of the most frequent complications for cancer
patients. Stereotactic radiosurgery is considered a cornerstone treatment for patients with …