Oxidative stress-related canonical pyroptosis pathway, as a target of liver toxicity triggered by zinc oxide nanoparticles

X Pei, H Jiang, C Li, D Li, S Tang - Journal of Hazardous Materials, 2023 - Elsevier
Abstract Zinc oxide nanoparticles (ZnO NPs) have been widely used in the fields of daily
necessities, clinical diagnosis, drug delivery and agricultural production. The improper use …

Engineered nanomaterials induce alterations in biological barriers: focus on paracellular permeability

LM Wang, YT Wang, WX Yang - Nanomedicine, 2021 - Taylor & Francis
Engineered nanoparticles (ENPs) are widely used in medical diagnosis and treatment, as
food additives and as energy materials. ENPs may exert adverse or beneficial effects on the …

[HTML][HTML] Zinc toxicity

UM Agnew, TL Slesinger - 2020 - europepmc.org
Objectives: Review the typical presentation of a patient with zinc toxicity. Describe the
management considerations for patients with zinc toxicity. Outline the treatment options for …

TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles

X Pei, D Liu, J Li, L Li, X Ding, W Zhang, Z Li… - Science of The Total …, 2023 - Elsevier
Abstract Zinc oxide nanoparticles (ZnO NPs) have drawn serious concerns about their
biotoxicity due to their extensive applications in biological medicine, clinical therapeutic …

[HTML][HTML] Metabolomics-directed nanotechnology in viral diseases management: COVID-19 a case study

MO El-Derany, DMF Hanna, J Youshia… - Pharmacological …, 2023 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently regarded
as the twenty-first century's plague accounting for coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Characterization, dose dependent assessment of hepatorenal oxidative stress, hematological parameters and histopathological divulging of the hepatic …

S Kausar, F Jabeen, MA Latif, M Asad - Saudi Journal of Biological …, 2023 - Elsevier
Nanoparticles are beneficial in many aspects to human life but their excessive use can
cause various abnormalities. They dispose in the environment through transport, industrial …

The protective effects of vitamins A, C, and E on zinc oxide nanoparticles (ZnO NPs)-induced liver oxidative stress in male Wistar rats

M Bayat, S Daei, N Ziamajidi… - Drug and Chemical …, 2023 - Taylor & Francis
The ever-increasing use of zinc oxide nanoparticles (ZnO NPs) in industrial and consumer
products leads to concerns about their safety. Liver is one of the most important target …

Protective effects of naringin on valproic acid-induced hepatotoxicity in rats

OF Koroglu, M Gunata, N Vardi, A Yildiz, B Ates… - Tissue and Cell, 2021 - Elsevier
Valproic acid (VPA) is mainly prescribed to treat epilepsy. VPA has been reported to be
associated with many adverse effects, including hepatotoxicity. Naringin (NRG) is a natural …

Paeoniflorin recued hepatotoxicity under zinc oxide nanoparticles exposure via regulation on gut-liver axis and reversal of pyroptosis

X Pei, S Tang, H Jiang, W Zhang, G Xu, Z Zuo… - Science of The Total …, 2023 - Elsevier
The risks of Zinc oxide nanoparticles (ZnO NPs) applications in biological medicine, food
processing industry, agricultural production and the biotoxicity brought by environmental …

Potential ecotoxicity of substrate-enriched zinc oxide nanoparticles to Physalaemus cuvieri tadpoles

AR Gomes, ATB Guimarães, LP de Matos… - Science of the Total …, 2023 - Elsevier
Although the ecotoxicological effects of ZnO nanoparticles (ZnO NPs) have already been
reported in different taxa, little is known about their impacts on amphibians. Thus, we aimed …