Current strategies to enhance adipose stem cell function: an update

Y Seo, TH Shin, HS Kim - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) emerged as a promising therapeutic tool targeting a variety
of inflammatory disorders due to their multiple remarkable properties, such as superior …

Mesenchymal stem cells for cardiac regeneration: from differentiation to cell delivery

S Gupta, A Sharma, RS Verma - Stem Cell Reviews and Reports, 2021 - Springer
Mesenchymal stem cells (MSCs) are so far the most widely researched stem cells in clinics
and used as an experimental cellular therapy module, particularly in cardiac regeneration …

Mesenchymal stem/stromal cells in organ transplantation

D Deo, M Marchioni, P Rao - Pharmaceutics, 2022 - mdpi.com
Organ transplantation is essential and crucial for saving and enhancing the lives of
individuals suffering from end-stage organ failure. Major challenges in the medical field …

Effect of Intramyocardial Administration of Baculovirus Encoding the Transcription Factor Tbx20 in Sheep With Experimental Acute Myocardial Infarction

MR Bauzá, AE López, JA Simonin… - Journal of the …, 2024 - ahajournals.org
Background Gene therapy has been proposed as a strategy to induce cardiac regeneration
following acute myocardial infarction (AMI). Given that Tbx20, a transcription factor of the T …

Genetically modified mesenchymal stromal cells: a cell-based therapy offering more efficient repair after myocardial infarction

C Xu, Y Xie, B Wang - Stem Cell Research & Therapy, 2024 - Springer
Myocardial infarction (MI) is a serious complication of coronary artery disease. This condition
is common worldwide and has a profound impact on patients' lives and quality of life …

High-Throughput Production of Microcapsules for Human Bone Marrow Derived Mesenchymal Stem Cell Biomanufacturing in a Vertical-Wheel Bioreactor

M Teryek, P Jadhav, R Bento, B Parekkadan - … and Bioprocess Engineering, 2023 - Springer
Microencapsulation of human mesenchymal stromal cells (MSCs) via electrospraying has
been well documented in tissue engineering and regenerative medicine. Herein, we report …

TBX20 inhibits colorectal cancer tumorigenesis by impairing NHEJ‐mediated DNA repair

J Luo, JW Chen, J Zhou, K Han, S Li, JL Duan… - Cancer …, 2022 - Wiley Online Library
DNA high methylation is one of driving force for colorectal carcinoma (CRC) pathogenesis.
Transcription factors (TFs) can determine cell fate and play fundamental roles in multistep …

β‐Adrenergic stimuli and rotating suspension culture enhance conversion of human adipogenic mesenchymal stem cells into highly conductive cardiac progenitors

JF Islas, R Abbasgholizadeh, C Dacso… - Journal of Tissue …, 2020 - Wiley Online Library
Clinical trials using human adipogenic mesenchymal stem cells (hAdMSCs) for the
treatment of cardiac diseases have shown improvement in cardiac function and were proven …

Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis

GB Liu, YX Cheng, HM Li, Y Liu… - Molecular …, 2023 - spandidos-publications.com
Adipose tissue‑derived mesenchymal stem cells (ADMSCs) differentiate into cardiomyocytes
and may be an ideal cell source for myocardial regenerative medicine. Ghrelin is a gastric …

RNA-based strategies for cardiac reprogramming of human mesenchymal stromal cells

P Mueller, M Wolfien, K Ekat, CI Lang, D Koczan… - Cells, 2020 - mdpi.com
Multipotent adult mesenchymal stromal cells (MSCs) could represent an elegant source for
the generation of patient-specific cardiomyocytes needed for regenerative medicine …