[HTML][HTML] Hyaluronic acid: molecular mechanisms and therapeutic trajectory

RC Gupta, R Lall, A Srivastava, A Sinha - Frontiers in veterinary …, 2019 - frontiersin.org
Hyaluronic acid (also known as hyaluronan or hyaluronate) is naturally found in many
tissues and fluids, but more abundantly in articular cartilage and synovial fluid (SF) …

Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Hyaluronic acid in the third millennium

A Fallacara, E Baldini, S Manfredini, S Vertuani - Polymers, 2018 - mdpi.com
Since its first isolation in 1934, hyaluronic acid (HA) has been studied across a variety of
research areas. This unbranched glycosaminoglycan consisting of repeating disaccharide …

Multi‐functional liposome: a powerful theranostic nano‐platform enhancing photodynamic therapy

X Cheng, J Gao, Y Ding, Y Lu, Q Wei, D Cui… - Advanced …, 2021 - Wiley Online Library
Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion,
low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic …

From crosslinking strategies to biomedical applications of hyaluronic acid-based hydrogels: A review

Y Luo, J Tan, Y Zhou, Y Guo, X Liao, L He, D Li… - International journal of …, 2023 - Elsevier
Hyaluronic acid (HA) is not only a natural anionic polysaccharide with excellent
biocompatibility, biodegradability, and moisturizing effect, but also an essential factor that …

Hyaluronic acid-bilirubin nanomedicine-based combination chemoimmunotherapy

Y Lee, J Shinn, C Xu, HE Dobson, N Neamati… - Nature …, 2023 - nature.com
Despite significant advances in immune checkpoint blockade (ICB), immunosuppression
mediated by tumor-associated myeloid cells (TAMCs) poses a major barrier to cancer …

The extracellular matrix: its composition, function, remodeling, and role in tumorigenesis

K Dzobo, C Dandara - Biomimetics, 2023 - mdpi.com
The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …

Influence of hyaluronic acid modification on CD44 binding towards the design of hydrogel biomaterials

MY Kwon, C Wang, JH Galarraga, E Puré, L Han… - Biomaterials, 2019 - Elsevier
Hyaluronic acid (HA) is a linear polysaccharide of d-glucuronic acid and N-acetyl-d-
glucosamine that is native to many tissues and interacts with cells via cell-surface receptors …

Hyaluronic acid: incorporating the bio into the material

KJ Wolf, S Kumar - ACS biomaterials science & engineering, 2019 - ACS Publications
In the last few decades, hyaluronic acid (HA) has become increasingly employed as a
biomaterial in both clinical and research applications. The abundance of HA in many …

Metal-coordination synthesis of a natural injectable photoactive hydrogel with antibacterial and blood-aggregating functions for cancer thermotherapy and mild …

K Musaie, S Abbaszadeh, V Nosrati-Siahmazgi… - Biomaterials …, 2023 - pubs.rsc.org
Photothermal therapy (PTT) is a promising approach for treating cancer. However, it suffers
from the formation of local lesions and subsequent bacterial infection in the damaged area …