Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation

H Kang, MN Shokhirev, Z Xu, S Chandran… - Genes & …, 2020 - genesdev.cshlp.org
During mitosis, transcription of genomic DNA is dramatically reduced, before it is reactivated
during nuclear reformation in anaphase/telophase. Many aspects of the underlying …

Chondrogenic preconditioning of mesenchymal stem/stromal cells within a magnetic scaffold for osteochondral repair

J Zhang, M Zhang, R Lin, Y Du, L Wang, Q Yao… - …, 2022 - iopscience.iop.org
Stem cell therapy using mesenchymal stem/stromal cells (MSCs) represents a novel
approach to treating severe diseases, including osteoarthritis. However, the therapeutic …

Probiotic Propionibacterium freudenreichii MJ2 Enhances Osteoblast Differentiation and Mineralization by Increasing the OPG/RANKL Ratio

J Yeom, S Ma, YH Lim - Microorganisms, 2021 - mdpi.com
Osteoblast differentiation is important for the development of bone and the maintenance of
bone density. Propionibacterium freudenreichii is a probiotic with an anti-inflammatory …

Comparison of the translational potential of human mesenchymal progenitor cells from different bone entities for autologous 3D bioprinted bone grafts

AK Amler, PH Dinkelborg, D Schlauch… - International Journal of …, 2021 - mdpi.com
Reconstruction of segmental bone defects by autologous bone grafting is still the standard of
care but presents challenges including anatomical availability and potential donor site …

Osteoblast and stem cell response to nanoscale topographies: a review

NI Aminuddin, R Ahmad, SA Akbar… - … and Technology of …, 2016 - Taylor & Francis
To understand how cells respond to the nanoscale extracellular environment in vivo, cells
from various sources have been cultured on nanoscale patterns fabricated using bottom-up …

Loss of β‐Actin Leads to Accelerated Mineralization and Dysregulation of Osteoblast‐Differentiation Genes during Osteogenic Reprogramming

T Gjorgjieva, X Xie, P Commins, R Pasricha… - Advanced …, 2020 - Wiley Online Library
Actin plays fundamental roles in both the cytoplasm and the cell nucleus. In the nucleus, β‐
actin regulates neuronal reprogramming by consolidating a heterochromatin landscape …

NaOH-etched/boron-doped nanohydroxyapatite-coated PEEK implants enhance the proliferation and differentiation of osteogenic cells

T Gültan, MÇ Yurtsever… - Biomedical Materials, 2020 - iopscience.iop.org
The aim of the present study is to eliminate the bioinertness of polyetheretherketone (PEEK)
material and to increase its osteogenic activity by applying a number of surface …

Osteogenic differentiation of bone marrow mesenchymal stem cells on chitosan/gelatin scaffolds: gene expression profile and mechanical analysis

F Papadogiannis, A Batsali, ME Klontzas… - Biomedical …, 2020 - iopscience.iop.org
In the present study we explore the extracellular matrix (ECM) produced by human bone
marrow mesenchymal stem/stromal cells (BM-MSCs) induced to undergo osteogenic …

The Effect of Blood‐Derived Products on the Chondrogenic and Osteogenic Differentiation Potential of Adipose‐Derived Mesenchymal Stem Cells Originated from …

M Neubauer, O Kuten, C Stotter, K Kramer… - Stem Cells …, 2019 - Wiley Online Library
Background. Adipose‐derived mesenchymal stem cells (AD‐MSCs) from fat tissue
considered “surgical waste” during joint surgery may provide a potent source for …

From the Cover: Embryonic Exposure to TCDD Impacts Osteogenesis of the Axial Skeleton in Japanese medaka, Oryzias latipes

ALTD Watson, A Planchart, CJ Mattingly… - Toxicological …, 2017 - academic.oup.com
Recent studies from mammalian, fish, and in vitro models have identified bone and cartilage
development as sensitive targets for dioxins and other aryl hydrocarbon receptor ligands. In …