Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application

T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

Free radical lipid peroxidation: mechanisms and analysis

H Yin, L Xu, NA Porter - Chemical reviews, 2011 - ACS Publications
Oxygen is indispensable to metabolism and energy production for almost all life forms.
However, reactive oxygen species (ROS) generated from life processes can cause damage …

Functionalized DNA nanomaterials targeting toll‐like receptor 4 prevent bisphosphonate‐related osteonecrosis of the jaw via regulating mitochondrial homeostasis in …

T Zhang, H Ma, X Zhang, S Shi… - Advanced Functional …, 2023 - Wiley Online Library
Imbalance of macrophage polarization characterized by an increase in the percentage of
pro‐inflammatory M1 macrophages and a decrease in anti‐inflammatory M2 macrophages …

DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury

D Jiang, Z Ge, HJ Im, CG England, D Ni… - Nature biomedical …, 2018 - nature.com
Patients with acute kidney injury (AKI) frequently require kidney transplantation and
supportive therapies, such as rehydration and dialysis. Here, we show that radiolabelled …

The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings

GG Graham, MJ Davies, RO Day, A Mohamudally… - …, 2013 - Springer
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of
action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors …

[HTML][HTML] Acute kidney injury due to rhabdomyolysis and renal replacement therapy: a critical review

N Petejova, A Martinek - Critical Care, 2014 - Springer
Rhabdomyolysis, a clinical syndrome caused by damage to skeletal muscle and release of
its breakdown products into the circulation, can be followed by acute kidney injury (AKI) as a …

Clinical trials in acute respiratory distress syndrome: challenges and opportunities

MA Matthay, DF McAuley, LB Ware - The Lancet Respiratory …, 2017 - thelancet.com
This year is the 50th anniversary of the first description of acute respiratory distress
syndrome (ARDS). Since then, much has been learned about the pathogenesis of lung …

Treating acute kidney injury with antioxidative black phosphorus nanosheets

J Hou, H Wang, Z Ge, T Zuo, Q Chen, X Liu, S Mou… - Nano …, 2020 - ACS Publications
Black phosphorus nanosheets (BPNSs) have been actively employed as nanomedicine
agents for photothermal and photodynamic therapy by virtue of their unique optical …

Rhabdomyolysis

JL Zimmerman, MC Shen - Chest, 2013 - Elsevier
Rhabdomyolysis is a well-known clinical syndrome of muscle injury associated with
myoglobinuria, electrolyte abnormalities, and often acute kidney injury (AKI). The …

Mechanisms of haemolysis-induced kidney injury

K Van Avondt, E Nur, S Zeerleder - Nature Reviews Nephrology, 2019 - nature.com
Intravascular haemolysis is a fundamental feature of chronic hereditary and acquired
haemolytic anaemias, including those associated with haemoglobinopathies, complement …