BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

BACKGROUND Male infertility affects> 20 million men worldwide and represents a major
health concern. Although multifactorial, male infertility has a strong genetic basis which has …

During sexual reproduction, two haploid gametes fuse to form the zygote, and the acrosome
is essential to this fusion process (fertilization) in animals. The acrosome is a special kind of …

A number of long coiled-coil proteins are present on the Golgi. Often referred to as “golgins,”
they are well conserved in evolution and at least five are likely to have been present in the …

Semen sample with poor sperm motility, which called asthenozoospermia, is considered as
one of the main factors contributing to male infertility. Recognition of the cellular and …

Spermatogenesis is a prolonged and highly ordered physiological process that produces
haploid male germ cells through more than 40 steps and experiences dramatic …

The omnipresent ubiquitin–proteasome system (UPS) is an ATP-dependent enzymatic
machinery that targets substrate proteins for degradation by the 26S proteasome by tagging …

Global climate change and heat waves are sources of stress which fish are facing in the wild
as well as in aquaculture context. In coping with important environmental variations, they …

Sperm differentiation encompasses a complex sequence of morphological changes that
takes place in the seminiferous epithelium. In this process, haploid round spermatids …

Asthenoteratospermia is a common cause of male infertility. Recent studies have revealed
that CFAP65 mutations lead to severe asthenoteratospermia due to acrosome hypoplasia …