Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural product …, 2017 - pubs.rsc.org
Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382–431 This review covers the
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …

Uncovering potential applications of cyanobacteria and algal metabolites in biology, agriculture and medicine: current status and future prospects

R Singh, P Parihar, M Singh, A Bajguz… - Frontiers in …, 2017 - frontiersin.org
Cyanobacteria and algae having complex photosynthetic systems can channelize absorbed
solar energy into other forms of energy for production of food and metabolites. In addition …

Dereplication of microbial metabolites through database search of mass spectra

H Mohimani, A Gurevich, A Shlemov… - Nature …, 2018 - nature.com
Natural products have traditionally been rich sources for drug discovery. In order to clear the
road toward the discovery of unknown natural products, biologists need dereplication …

Harmful cyanobacterial blooms: causes, consequences, and controls

HW Paerl, TG Otten - Microbial ecology, 2013 - Springer
Cyanobacteria are the Earth's oldest oxygenic photoautotrophs and have had major impacts
on shaping its biosphere. Their long evolutionary history (∼ 3.5 by) has enabled them to …

Bloom dynamics of cyanobacteria and their toxins: environmental health impacts and mitigation strategies

RP Rastogi, D Madamwar… - Frontiers in microbiology, 2015 - frontiersin.org
Cyanobacteria are ecologically one of the most prolific groups of phototrophic prokaryotes in
both marine and freshwater habitats. Both the beneficial and detrimental aspects of …

Natural product biosynthetic diversity and comparative genomics of the cyanobacteria

E Dittmann, M Gugger, K Sivonen, DP Fewer - Trends in microbiology, 2015 - cell.com
Cyanobacteria are an ancient lineage of slow-growing photosynthetic bacteria and a prolific
source of natural products with intricate chemical structures and potent biological activities …

The biosynthetic logic of polyketide diversity

C Hertweck - Angewandte Chemie International Edition, 2009 - Wiley Online Library
Abstract Molecular Lego: Polyketides represent a highly diverse group of natural products
with structurally intriguing carbon skeletons (see picture) which are assembled from simple …

Cyanobacterial bioactive metabolites—A review of their chemistry and biology

IS Huang, PV Zimba - Harmful algae, 2019 - Elsevier
Cyanobacterial blooms occur when algal densities exceed baseline population
concentrations. Cyanobacteria can produce a large number of secondary metabolites …

Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis

RF Little, C Hertweck - Natural Product Reports, 2022 - pubs.rsc.org
Review covering up to mid-2021 The structure of polyketide and non-ribosomal peptide
natural products is strongly influenced by how they are released from their biosynthetic …

Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: logic, machinery, and mechanisms

MA Fischbach, CT Walsh - Chemical reviews, 2006 - ACS Publications
Many thousands of small molecule natural products with interesting biological activities are
polyketides (PK), nonribosomal peptides (NRP), or hybrids thereof (ie, PK-NRP hybrids) …