Higher-order epistasis shapes natural variation in germ stem cell niche activity
SR Fausett, A Sandjak, B Billard, C Braendle - Nature Communications, 2023 - nature.com
To study how natural allelic variation explains quantitative developmental system variation,
we characterized natural differences in germ stem cell niche activity, measured as …
we characterized natural differences in germ stem cell niche activity, measured as …
DOS-3 mediates cell-non-autonomous DAF-16/FOXO activity in antagonizing age-related loss of C. elegans germline stem/progenitor cells
Z Zhang, H Yang, L Fang, G Zhao, J Xiang… - Nature …, 2024 - nature.com
Age-related depletion of stem cells causes tissue degeneration and failure to tissue
regeneration, driving aging at the organismal level. Previously we reported a cell-non …
regeneration, driving aging at the organismal level. Previously we reported a cell-non …
Aging, Fast and Slow: Gene Expression Signatures of Physiological Age vs. Future Lifespan in Caenorhabditis elegans
MC Mosley - 2024 - search.proquest.com
An outstanding question in the field of aging biology is the origin of variability in lifespans
among members of the same species. Traditional wisdom dictates that differences in one …
among members of the same species. Traditional wisdom dictates that differences in one …