Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

Depression is one of the leading causes of disability, and, if left unmanaged, it can increase
the risk for suicide. The evidence base on the determinants of depression is fragmented …

Despite numerous studies on the neurobiology of depression, the etiological and
pathophysiological mechanisms of this disorder remain poorly understood. A large number …

Major depressive disorder (MDD) is currently the main cause of disability worldwide, but its
pathophysiology remains largely unknown, especially given its high heterogeneity in terms …

Speech carries essential information about the speaker's physiology and possible
pathophysiological conditions. Bio-acoustic voice qualities show promising value for …

Major depressive disorder (MDD) is a common mental disorder generally characterized by
symptoms associated with mood, pleasure and effectiveness in daily life activities. MDD is …

Major depression (MD) is a complex, heterogeneous neuropsychiatric disorder. An early
age at onset of major depression (AAO-MD) has been associated with more severe illness …

Background Major depressive disorder (MDD) is a common psychiatric disorder associated
with a high disease burden. This study gives a comprehensive overview of the prevalence …

Nutrition and metabolism modify epigenetic signatures like histone acetylation and DNA
methylation. Histone acetylation and DNA methylation in the central nervous system (CNS) …

Objective: Major depressive disorder (MDD) is highly heterogeneous. Standard typology
partly captures the disorder's symptomatic heterogeneity, although whether it adequately …