MOG encephalomyelitis: international recommendations on diagnosis and antibody testing

S Jarius, F Paul, O Aktas, N Asgari, RC Dale… - Journal of …, 2018 - Springer
Over the past few years, new-generation cell-based assays have demonstrated a robust
association of autoantibodies to full-length human myelin oligodendrocyte glycoprotein …

Myelin oligodendrocyte glycoprotein antibodies in neurological disease

M Reindl, P Waters - Nature Reviews Neurology, 2019 - nature.com
Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Abs) were first detected
by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their …

Clinical spectrum and prognostic value of CNS MOG autoimmunity in adults: the MOGADOR study

A Cobo-Calvo, A Ruiz, E Maillart, B Audoin, H Zephir… - Neurology, 2018 - AAN Enterprises
Objective To describe clinical and radiologic features associated with myelin
oligodendrocyte glycoprotein antibodies (MOG-Ab) in a large French nationwide adult …

Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient

T Cellucci, H Van Mater, F Graus, E Muscal… - Neurology …, 2020 - AAN Enterprises
Objective Autoimmune encephalitis (AE) is an important and treatable cause of acute
encephalitis. Diagnosis of AE in a developing child is challenging because of overlap in …

Acute disseminated encephalomyelitis and acute hemorrhagic leukoencephalitis following COVID-19: systematic review and meta-synthesis

GS Manzano, CRS McEntire… - Neurology …, 2021 - AAN Enterprises
Background and Objectives Since the onset of the COVID-19 pandemic, a growing number
of reports have described cases of acute disseminated encephalomyelitis (ADEM) and acute …

B cells in autoimmune and neurodegenerative central nervous system diseases

JJ Sabatino Jr, AK Pröbstel, SS Zamvil - Nature Reviews Neuroscience, 2019 - nature.com
B cells are essential components of the adaptive immune system and have important roles
in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …

Association of MOG-IgG serostatus with relapse after acute disseminated encephalomyelitis and proposed diagnostic criteria for MOG-IgG–associated disorders

AS López-Chiriboga, M Majed, J Fryer, D Dubey… - JAMA …, 2018 - jamanetwork.com
Importance Recent studies have reported a higher relapse rate following an initial
inflammatory demyelinating disorder in pediatric patients with persistent seropositivity of …

Clinical features and risk of relapse in children and adults with myelin oligodendrocyte glycoprotein antibody–associated disease

A Cobo‐Calvo, A Ruiz, F Rollot… - Annals of …, 2021 - Wiley Online Library
Objective The main objective was to compare clinical features, disease course, and myelin
oligodendrocyte glycoprotein (MOG) antibody (Ab) dynamics between children and adults …

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: frequency, syndrome specificity, influence of disease activity, long-term course …

S Jarius, K Ruprecht, I Kleiter, N Borisow… - Journal of …, 2016 - Springer
Background Antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) have been
suggested to play a role in a subset of patients with neuromyelitis optica and related …

Prognostic relevance of MOG antibodies in children with an acquired demyelinating syndrome

EM Hennes, M Baumann, K Schanda, B Anlar… - Neurology, 2017 - AAN Enterprises
Objective: To assess the prognostic value of MOG antibodies (abs) in the differential
diagnosis of acquired demyelinating syndromes (ADS). Methods: Clinical course, MRI, MOG …