Skin cancer is the most common type of cancer in the US with an increasing prevalence
worldwide. While ultraviolet (UV) radiation is a well-known risk factor, there is emerging …

ABSTRACT IL-17 is produced by RAR-related orphan receptor gamma t (RORγt)-expressing
cells including Th17 cells, subsets of γδT cells and innate lymphoid cells (ILCs). The …

Multimodal single-cell assays provide high-resolution snapshots of complex cell
populations, but are mostly limited to transcriptome plus an additional modality. Here, we …

It has been proposed that CD4 T-cell responses to Staphylococcus aureus (SA) can
inadvertently enhance neoplastic progression in models of skin cancer and cutaneous T-cell …

Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of mature T-cell neoplasms
characterized by the accumulation of clonal malignant CD4+ T cells in the skin. The most …

Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of lymphoproliferative
neoplasms that exhibit a wide spectrum of immune-phenotypical, clinical, and …

Staphylococcus aureus is suspected to fuel disease activity in cutaneous T-cell lymphomas.
In this study, we investigate the effect of a recombinant, antibacterial protein, endolysin (XZ …

Leukemic cutaneous T‐cell lymphomas (L‐CTCL) are lymphoproliferative disorders of skin‐
homing mature T‐cells causing severe symptoms and high mortality through chronic …

Cells are the fundamental units of biological systems and exhibit unique development
trajectories and molecular features. Our exploration of how the genomes orchestrate the …

Cutaneous T-cell lymphoma (CTCL) is a devastating lymphoid malignancy characterized by
the accumulation of malignant T cells in the dermis and epidermis. Skin lesions cause …