Recent progress in bioconjugation strategies for liposome-mediated drug delivery

B Almeida, OK Nag, KE Rogers, JB Delehanty - Molecules, 2020 - mdpi.com
In nanoparticle (NP)-mediated drug delivery, liposomes are the most widely used drug
carrier, and the only NP system currently approved by the FDA for clinical use, owing to their …

Recent advances in ruthenium (II) and iridium (III) complexes containing nanosystems for cancer treatment and bioimaging

J Shen, TW Rees, L Ji, H Chao - Coordination chemistry reviews, 2021 - Elsevier
Ruthenium (II) and iridium (III) coordination compounds display excellent structural,
photophysical, and biological properties which make them highly promising as anticancer …

Neuronal mitochondria-targeted micelles relieving oxidative stress for delayed progression of Alzheimer's disease

P Yang, D Sheng, Q Guo, P Wang, S Xu, K Qian, Y Li… - Biomaterials, 2020 - Elsevier
Mitochondrial dysfunction is an early event of Alzheimer's disease (AD), contributes the
onset and progression of AD, and may represent an effective therapeutic target for AD …

Construction of homo and heteronuclear Ru (II), Ir (III) and Re (I) complexes for target specific cancer therapy

S Pete, N Roy, B Kar, P Paira - Coordination Chemistry Reviews, 2022 - Elsevier
More than 10 million death tolls in 2020 were reported as a result of heinous impact of
cancer, making it second most prime cause of death after cardiovascular diseases. In …

[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies

S Adhikari, P Nath, A Das, A Datta, N Baildya… - Biomedicine & …, 2024 - Elsevier
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

Versatile delivery systems for non-platinum metal-based anticancer therapeutic agents

Y Gou, GJ Huang, J Li, F Yang, H Liang - Coordination chemistry reviews, 2021 - Elsevier
Platinum-based anticancer drugs currently available in the market are associated with
severe side effects. Therefore, extensive research has been performed to design and …

Antitumor Effects of Ir(III)-2H-Indazole Complexes for Triple Negative Breast Cancer

RL Panchangam, RN Rao, MM Balamurali… - Inorganic …, 2021 - ACS Publications
In this work, we have synthesized a series of novel C, N-cyclometalated 2 H-indazole-
ruthenium (II) and-iridium (III) complexes with varying substituents (H, CH3, isopropyl, and …

Metal complex-based liposomes: Applications and prospects in cancer diagnostics and therapeutics

Z Wang, J Li, G Lin, Z He, Y Wang - Journal of Controlled Release, 2022 - Elsevier
Metal complexes are of increasing interest as pharmaceutical agents in cancer diagnostics
and therapeutics, while some of them suffer from issues such as limited water solubility and …

Formulation, Optimization, and Evaluation of Moringa oleifera Leaf Polyphenol-Loaded Phytosome Delivery System against Breast Cancer Cell Lines

J Wanjiru, J Gathirwa, E Sauli, HS Swai - Molecules, 2022 - mdpi.com
Moringa oleifera leaf polyphenols (Mopp) were encapsulated with phytosomes to enhance
their efficacy on 4T1 cancer cell lines. The Mopp were extracted via microwave-assisted …

Advances in novel iridium (III) based complexes for anticancer applications: A review

A Sharma, P Sudhindra, N Roy, P Paira - Inorganica Chimica Acta, 2020 - Elsevier
The need to synthesize an effective anticancer drug with minimal side effects has been the
aim and concern of the researchers around the world. Cytotoxicity and selectivity are the two …