Advanced material technologies for space and terrestrial medicine
The medical risks of spaceflight are amplified as humans venture into longer-duration and
greater-distance deep space voyages. During space missions, astronauts face the extremes …
greater-distance deep space voyages. During space missions, astronauts face the extremes …
Carbon fiber reinforced polymers for implantable medical devices
Carbon fibers reinforced polymers (CFRPs) are prolifically finding applications in the
medical field, moving beyond the aerospace and automotive industries. Owing to its high …
medical field, moving beyond the aerospace and automotive industries. Owing to its high …
Strategic aspects of space medicine: A journey from conventional to futuristic requisites
A Wani, B Prabhakar, P Shende - Space: Science & Technology, 2024 - spj.science.org
Space-travel system comes with a number of difficulties that endanger the astronauts'
survival in the intensely radiative environment by adversely affecting their physiological …
survival in the intensely radiative environment by adversely affecting their physiological …
Bisphosphonate conjugation enhances the bone-specificity of NELL-1-based systemic therapy for spaceflight-induced bone loss in mice
Microgravity-induced bone loss results in a 1% bone mineral density loss monthly and can
be a mission critical factor in long-duration spaceflight. Biomolecular therapies with dual …
be a mission critical factor in long-duration spaceflight. Biomolecular therapies with dual …
Space medicines for space health
QD Tran, V Tran, LS Toh, PM Williams… - ACS Medicinal …, 2022 - ACS Publications
Scientists from around the world are studying the effects of microgravity and cosmic radiation
via the “off-Earth” International Space Station (ISS) laboratory platform. The ISS has helped …
via the “off-Earth” International Space Station (ISS) laboratory platform. The ISS has helped …
Extending drug release from implants via transcutaneous refilling with solid therapeutics
Long‐acting (LA) implantable drug delivery systems (IDDS) offer an effective approach for
the management or prevention of chronic conditions by sustained parenteral therapeutic …
the management or prevention of chronic conditions by sustained parenteral therapeutic …
Silicon nanofluidic membrane for electrostatic control of drugs and analytes elution
Individualized long-term management of chronic pathologies remains an elusive goal
despite recent progress in drug formulation and implantable devices. The lack of advanced …
despite recent progress in drug formulation and implantable devices. The lack of advanced …
An integrative network science and artificial intelligence drug repurposing approach for muscle atrophy in spaceflight microgravity
V Manian, J Orozco-Sandoval… - Frontiers in Cell and …, 2021 - frontiersin.org
Muscle atrophy is a side effect of several terrestrial diseases which also affects astronauts
severely in space missions due to the reduced gravity in spaceflight. An integrative graph …
severely in space missions due to the reduced gravity in spaceflight. An integrative graph …
Viral load reduction in SHIV-positive nonhuman primates via long-acting subcutaneous tenofovir alafenamide fumarate release from a nanofluidic implant
HIV-1 is a chronic disease managed by strictly adhering to daily antiretroviral therapy (ART).
However, not all people living with HIV-1 have access to ART, and those with access may …
However, not all people living with HIV-1 have access to ART, and those with access may …
Silicon carbide-gated nanofluidic membrane for active control of electrokinetic ionic transport
Manipulation of ions and molecules by external control at the nanoscale is highly relevant to
biomedical applications. We report a biocompatible electrode-embedded nanofluidic …
biomedical applications. We report a biocompatible electrode-embedded nanofluidic …