Gliomas are the most common malignant primary brain tumors, of which glioblastoma is the
most malignant form (WHO grade IV), and notorious for treatment resistance. Over the last …

Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

Epigenetic mechanisms, which include DNA methylation, a variety of post-translational
modifications of histone proteins (acetylation, phosphorylation, methylation, ubiquitination …

Understanding the cellular and molecular mechanisms underlying the formation and
maintenance of memories is a central goal of the neuroscience community. It is well …

Many environmental toxicants have been shown to be associated with the transgenerational
inheritance of increased disease susceptibility. This review describes the generational …

Pain is an unpleasant but essential-to-life sensation, usually resulting from tissue damage.
When pain persists long after the injury has resolved, it becomes pathological. The precise …

Epigenetics is the study of heritable and stable changes in gene expression that occur
through alterations in the chromosome rather than in the DNA sequence. Despite not directly …

The current evolutionary biology theory primarily involves genetic alterations and random
DNA sequence mutations to generate the phenotypic variation required for Darwinian …

Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

Due to a blood supply shortage, articular cartilage has a limited capacity for self-healing
once damaged. Articular chondrocytes, cartilage progenitor cells, embryonic stem cells, and …