Cuproptosis was a copper-dependent and unique kind of cell death that was separate from
existing other forms of cell death. The last decade has witnessed a considerable increase in …

Many types of human cells self-destruct to maintain biological homeostasis and defend the
body against pathogenic substances. This process, called regulated cell death (RCD), is …

Copper is an essential micronutrient for human body and plays a vital role in various
biological processes including cellular respiration and free radical detoxification. Generally …

Breast cancer is one of the most common malignant tumors in women worldwide, and thus, it
is important to enhance its treatment efficacy [1]. Copper has emerged as a critical trace …

Cell death is involved in a wide range of physiological and pathological processes.
Recently, the term “cuproptosis” was coined to describe a novel type of cell death. This type …

Cuproptosis, a new type of programmed cell death (PCD), is closely related to cellular
tricarboxylic acid cycle and cellular respiration, while hypoxia can modulate PCD. However …

Cuproptosis is a novel cell death mechanism caused by copper overload, with FDX1 serving
as the key regulator. LncRNAs are known to play a significant role in the aberrant regulation …

Copper, a vital trace element, orchestrates diverse cellular processes ranging from energy
production to antioxidant defense and angiogenesis. Copper metabolism and cuproptosis …

DLD is a key gene involved in “cuproptosis,” but its roles in tumor progression and immunity
remain unclear. Exploring the potential mechanisms and biological roles of DLD may …

Copper is an important metal micronutrient, required for the balanced growth and normal
physiological functions of human organism. Copper-related toxicity and dysbalanced …