Significance: An abundance of experimental evidence suggests that hydrogen sulfide (H2S)
plays a prominent role in physiology and pathophysiology. Many targets exist for H2S …

Reactive oxygen species (ROS) are considered to be chemically reactive with and
damaging to biomolecules including DNA, protein, and lipid, and excessive exposure to …

Peripheral arterial disease (PAD) increases the risk of lower extremity amputation. It is also
an independent predictor of cardiovascular and cerebrovascular ischemic events, affecting …

Background The vascular safety of electronic cigarettes (e-Cigarettes) must still be clarified.
We compared the impact of e-Cigarettes vs traditional tobacco cigarettes on oxidative stress …

Background Little clinical research on new‐generation heat‐not‐burn cigarettes (HNBC) in
comparison with electronic vaping cigarettes (EVC) and traditional tobacco combustion …

Abstract Significance: 8-Hydroxy-2-deoxyguanosine (8-OHdG) is generated after the repair
of ROS-mediated DNA damages and, thus, is one of the most widely recognized biomarkers …

Background: Troponins may be elevated in patients with pneumonia, but associations with
myocardial infarction (MI) and with platelet activation are still undefined. Objectives: The aim …

Damage to the genome is recognized as a fundamental cause of developmental and
degenerative diseases. Several micronutrients play an important role in protecting against …

Peripheral artery disease (PAD) is an atherosclerotic disease characterized by a narrowing
of the arteries in the lower extremities. Disease manifestations are the result of more than …

Atherosclerotic arterial occlusive disease affecting the lower extremities is also known as
peripheral artery disease (PAD). This disorder affects 8 to 12 million individuals in the US …