Nanopores: A journey towards DNA sequencing

M Wanunu - Physics of life reviews, 2012 - Elsevier
Much more than ever, nucleic acids are recognized as key building blocks in many of lifeʼs
processes, and the science of studying these molecular wonders at the single-molecule …

Single molecule sensing with solid-state nanopores: novel materials, methods, and applications

BN Miles, AP Ivanov, KA Wilson, F Doğan… - Chemical Society …, 2013 - pubs.rsc.org
This tutorial review will introduce and explore the fundamental aspects of nanopore (bio)
sensing, fabrication, modification, and the emerging technologies and applications that both …

Identification of single nucleotides in MoS2 nanopores

J Feng, K Liu, RD Bulushev, S Khlybov… - Nature …, 2015 - nature.com
The size of the sensing region in solid-state nanopores is determined by the size of the pore
and the thickness of the pore membrane, so ultrathin membranes such as graphene and …

Detecting the translocation of DNA through a nanopore using graphene nanoribbons

F Traversi, C Raillon, SM Benameur, K Liu… - Nature …, 2013 - nature.com
Solid-state nanopores can act as single-molecule sensors and could potentially be used to
rapidly sequence DNA molecules. However, nanopores are typically fabricated in insulating …

Identifying single nucleotides by tunnelling current

M Tsutsui, M Taniguchi, K Yokota, T Kawai - Nature nanotechnology, 2010 - nature.com
A major goal in medical research is to develop a DNA sequencing technique that is capable
of reading an entire human genome at low cost,,,. Recently, it was proposed that DNA …

DNA origami nanopores

NAW Bell, CR Engst, M Ablay, G Divitini, C Ducati… - Nano …, 2012 - ACS Publications
We demonstrate the assembly of functional hybrid nanopores for single molecule sensing by
inserting DNA origami structures into solid-state nanopores. In our experiments, single …

Local electrical potential detection of DNA by nanowire–nanopore sensors

P Xie, Q Xiong, Y Fang, Q Qing, CM Lieber - Nature nanotechnology, 2012 - nature.com
Nanopores could potentially be used to perform single-molecule DNA sequencing at low
cost and with high throughput,,,. Although single base resolution and differentiation have …

Polymer translocation: the first two decades and the recent diversification

VV Palyulin, T Ala-Nissila, R Metzler - Soft matter, 2014 - pubs.rsc.org
Probably no other field of statistical physics at the borderline of soft matter and biological
physics has caused such a flurry of papers as polymer translocation since the 1994 …

Plasmonic nanopores for trapping, controlling displacement, and sequencing of DNA

M Belkin, SH Chao, MP Jonsson, C Dekker… - ACS …, 2015 - ACS Publications
With the aim of developing a DNA sequencing methodology, we theoretically examine the
feasibility of using nanoplasmonics to control the translocation of a DNA molecule through a …

Controlling molecular transport through nanopores

UF Keyser - Journal of The Royal Society Interface, 2011 - royalsocietypublishing.org
Nanopores are emerging as powerful tools for the detection and identification of
macromolecules in aqueous solution. In this review, we discuss the recent development of …