Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease

G De Rubis, KR Paudel, L Corrie, S Mehndiratta… - Naunyn-Schmiedeberg's …, 2024 - Springer
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …

Engineered liposomes in interventional theranostics of solid tumors

N Kommineni, R Chaudhari, J Conde… - ACS Biomaterials …, 2023 - ACS Publications
Engineered liposomal nanoparticles have unique characteristics as cargo carriers in cancer
care and therapeutics. Liposomal theranostics have shown significant progress in preclinical …

Fecal microbiota transplantation in liver cirrhosis

A Boicean, V Birlutiu, C Ichim, O Brusnic, DM Onișor - Biomedicines, 2023 - mdpi.com
The human gastrointestinal tract houses a diverse array of probiotic and pathogenic bacteria
and any alterations in this microbial composition can exert a significant influence on an …

Interplay of gut microbiota in polycystic ovarian syndrome: role of gut microbiota, mechanistic pathways and potential treatment strategies

L Corrie, A Awasthi, J Kaur, S Vishwas, M Gulati… - Pharmaceuticals, 2023 - mdpi.com
Polycystic Ovarian Syndrome (PCOS) comprises a set of symptoms that pose significant risk
factors for various diseases, including type 2 diabetes, cardiovascular disease, and cancer …

Harnessing the dual role of polysaccharides in treating gastrointestinal diseases: As therapeutics and polymers for drug delivery

L Corrie, M Gulati, A Awasthi, S Vishwas, J Kaur… - Chemico-Biological …, 2022 - Elsevier
Polysaccharides (PS) represent a broad class of polymer-based compounds that have been
extensively researched as therapeutics and excipients for drug delivery. As pharmaceutical …

Development of guar gum-pectin-based colon targeted solid self-nanoemulsifying drug delivery system of xanthohumol

M Hanmantrao, S Chaterjee, R Kumar, S Vishwas… - Pharmaceutics, 2022 - mdpi.com
Present study deciphers development of oral polysaccharide-based colon targeted solid self-
nanoemulsifying drug delivery system (S-SNEDDS) of xanthohumol (XH). Several studies …

Hyaluronic Acid Modified Metal Nanoparticles and Their Derived Substituents for Cancer Therapy: A Review

UT Uthappa, M Suneetha, KV Ajeya, SM Ji - Pharmaceutics, 2023 - mdpi.com
The use of metal nanoparticles (M-NPs) in cancer therapy has gained significant
consideration owing to their exceptional physical and chemical features. However, due to …

Research progress of colon-targeted oral hydrogel system based on natural polysaccharides

D Wang, W Wang, P Wang, C Wang, J Niu, Y Liu… - International journal of …, 2023 - Elsevier
The quality of life is significantly impacted by colon-related diseases. There have been a lot
of interest in the oral colon-specific drug delivery system (OCDDS) as a potential carrier to …

HPMCAS-Based Amorphous Solid Dispersions in Clinic: A Review on Manufacturing Techniques (Hot Melt Extrusion and Spray Drying), Marketed Products and …

L Corrie, S Ajjarapu, S Banda, M Parvathaneni… - Materials, 2023 - mdpi.com
Today, therapeutic candidates with low solubility have become increasingly common in
pharmaceutical research pipelines. Several techniques such as hot melt extrusion, spray …

Polysaccharide-fecal microbiota-based colon-targeted self-nanoemulsifying drug delivery system of curcumin for treating polycystic ovarian syndrome

L Corrie, H Singh, M Gulati, S Vishwas… - Naunyn-Schmiedeberg's …, 2024 - Springer
The gut microbiome is involved in the pathogenesis of many diseases including polycystic
ovarian syndrome (PCOS). Modulating the gut microbiome can lead to eubiosis and …