Left ventricular non-compaction, the most recently classified form of cardiomyopathy, is
characterised by abnormal trabeculations in the left ventricle, most frequently at the apex. It …

Left ventricular noncompaction (LVNC) describes a ventricular wall anatomy characterized
by prominent left ventricular (LV) trabeculae, a thin compacted layer, and deep …

Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium
not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a …

Hypertrophic cardiomyopathy (HCM) was traditionally described as an autosomal dominant
Mendelian disease but is now increasingly recognized as having a complex genetic …

Left ventricular hypertrabeculation (LVHT) or noncompaction is a myocardial abnormality of
unknown aetiology, frequently associated with monogenic disorders, particularly …

Background—Yield of causative variants in hypertrophic cardiomyopathy (HCM) is
increased in some probands, suggesting different clinical subgroups of disease occur. We …

Hypertrophic cardiomyopathy (HCM) is a cardiac genetic disease accompanied by structural
and contractile alterations. We identified a rare c. 740C> T (p. T247M) mutation in ACTN 2 …

Background—Left ventricular noncompaction (LVNC) is a genetically and phenotypically
heterogeneous disease and, although increasingly recognized in clinical practice, there is a …

Background Genetic testing following sudden cardiac death (SCD) is currently guided by
autopsy findings, despite the inherent challenges of autopsy examination and mounting …

Background A genetic cause can be identified in 30% of noncompaction cardiomyopathy
patients (NCCM) with clinical features ranging from asymptomatic cardiomyopathy to heart …