Medial prefrontal cortex in neurological diseases

P Xu, A Chen, Y Li, X Xing, H Lu - Physiological genomics, 2019 - journals.physiology.org
The medial prefrontal cortex (mPFC) is a crucial cortical region that integrates information
from numerous cortical and subcortical areas and converges updated information to output …

The role of gamma oscillations in central nervous system diseases: Mechanism and treatment

A Guan, S Wang, A Huang, C Qiu, Y Li, X Li… - Frontiers in cellular …, 2022 - frontiersin.org
Gamma oscillation is the synchronization with a frequency of 30–90 Hz of neural
oscillations, which are rhythmic electric processes of neuron groups in the brain. The …

What is resilience: an affiliative neuroscience approach

R Feldman - World psychiatry, 2020 - Wiley Online Library
Resilience–a key topic in clinical science and practice–still lacks a clear conceptualization
that integrates its evolutionary and human‐specific features, refrains from exclusive focus on …

Adolescent sleep shapes social novelty preference in mice

WJ Bian, CL Brewer, JA Kauer, L de Lecea - Nature neuroscience, 2022 - nature.com
Sleep disturbances frequently occur in neurodevelopmental disorders such as autism, but
the developmental role of sleep is largely unexplored, and a causal relationship between …

Rescue of oxytocin response and social behaviour in a mouse model of autism

H Hörnberg, E Pérez-Garci, D Schreiner… - Nature, 2020 - nature.com
A fundamental challenge in developing treatments for autism spectrum disorders is the
heterogeneity of the condition. More than one hundred genetic mutations confer high risk for …

The plasticitome of cortical interneurons

AR McFarlan, CYC Chou, A Watanabe… - Nature Reviews …, 2023 - nature.com
Hebb postulated that, to store information in the brain, assemblies of excitatory neurons
coding for a percept are bound together via associative long-term synaptic plasticity. In this …

Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition

C Zhang, H Zhu, Z Ni, Q Xin, T Zhou, R Wu, G Gao… - Neuron, 2022 - cell.com
Social competition plays a pivotal role in determining individuals' social status. While the
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

H Jung, H Park, Y Choi, H Kang, E Lee, H Kweon… - Nature …, 2018 - nature.com
Autism spectrum disorders (ASDs) are four times more common in males than in females,
but the underlying mechanisms are poorly understood. We characterized sexually dimorphic …

The gut microbiota regulates autism-like behavior by mediating vitamin B6 homeostasis in EphB6-deficient mice

Y Li, ZY Luo, YY Hu, YW Bi, JM Yang, WJ Zou, YL Song… - Microbiome, 2020 - Springer
Background Autism spectrum disorder (ASD) is a developmental disorder, and the effective
pharmacological treatments for the core autistic symptoms are currently limited. Increasing …

[HTML][HTML] Correlated neural activity across the brains of socially interacting bats

W Zhang, MM Yartsev - Cell, 2019 - cell.com
Social interactions occur between multiple individuals, but what is the detailed relationship
between the neural dynamics across their brains? To address this question across …