UK Biobank is a population-based cohort of half a million participants aged 40–69 years
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …

Normative modeling is an emerging and innovative framework for mapping individual
differences at the level of a single subject or observation in relation to a reference model. It …

Biological aging of human organ systems reflects the interplay of age, chronic disease,
lifestyle and genetic risk. Using longitudinal brain imaging and physiological phenotypes …

There is strong evidence of brain-related abnormalities in COVID-19,,,,,,,,,,,–. However, it
remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder …

UK Biobank is a major prospective epidemiological study, including multimodal brain
imaging, genetics and ongoing health outcomes. Previously, we published genome-wide …

Heavy alcohol consumption has been associated with brain atrophy, neuronal loss, and
poorer white matter fiber integrity. However, there is conflicting evidence on whether light-to …

Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …

Every year, millions of brain magnetic resonance imaging (MRI) scans are acquired in
hospitals across the world. These have the potential to revolutionize our understanding of …

Preprocessing of functional magnetic resonance imaging (fMRI) involves numerous steps to
clean and standardize the data before statistical analysis. Generally, researchers create ad …

The genetic architecture of brain structure and function is largely unknown. To investigate
this, we carried out genome-wide association studies of 3,144 functional and structural brain …