Neonicotinoids have been used to protect crops and animals from insect pests since the
1990s, but there are concerns regarding their adverse effects on nontarget organisms …

The GABA A receptors are the major inhibitory neurotransmitter receptors in mammalian
brain. Each isoform consists of five homologous or identical subunits surrounding a central …

▪ Abstract The neonicotinoids, the newest major class of insecticides, have outstanding
potency and systemic action for crop protection against piercing-sucking pests, and they are …

In this review we attempt to summarize experimental evidence on the existence of defined
native GABAA receptor subtypes and to produce a list of receptors that actually seem to exist …

This mini-review attempts to update experimental evidence on the existence of GABAA
receptor pharmacological subtypes and to produce a list of those native receptors that exist …

▪ Abstract Neonicotinoids, the most important new class of synthetic insecticides of the past
three decades, are used to control sucking insects both on plants and on companion …

Nicotinic receptors—a family of ligand-gated ion channels that mediate the effects of the
neurotransmitter acetylcholine—are among the most well understood allosteric membrane …

Imidacloprid is increasingly used worldwide as an insecticide. It is an agonist at nicotinic
acetylcholine receptors (nAChRs) and shows selective toxicity for insects over vertebrates …

We present a refined model of the membrane-associated Torpedo acetylcholine (ACh)
receptor at 4Å resolution. An improved experimental density map was obtained from 342 …

Pentameric ligand gated ion-channels, or Cys-loop receptors, mediate rapid chemical
transmission of signals. This superfamily of allosteric transmembrane proteins includes the …