Use of Lawesson's reagent in organic syntheses

T Ozturk, E Ertas, O Mert - Chemical reviews, 2007 - ACS Publications
Transformation of a carbonyl functional group into thiocarbonyl has been an important
interest to synthetic organic chemists for many years. Two reagents, phosphorus …

Pharmacological properties of furoxans and benzofuroxans: recent developments

H Cerecetto, W Porcal - Mini reviews in medicinal chemistry, 2005 - benthamdirect.com
The chemistry of furoxans (1, 2, 5-oxadiazole-2-oxides) and benzofuroxans (benzo [1, 2-c] 1,
2, 5-oxadiazole-1-oxides) is very well known. These systems are widely used in organic …

Quimioterapia da doença de Chagas: estado da arte e perspectivas no desenvolvimento de novos fármacos

LC Dias, MA Dessoy, JJN Silva, OH Thiemann… - Química …, 2009 - SciELO Brasil
Neglected diseases are a major global cause of illness, long-term disability and death.
Chagas' disease is a parasitic infection widely distributed throughout Latin America, with …

Synthesis and biological activities of oxadiazole derivatives: a review

A Vaidya, S Jain, P Jain, P Jain, N Tiwari… - Mini Reviews in …, 2016 - ingentaconnect.com
Recently, there has been wide interest in compounds containing the oxadiazole scaffold
because of their unique chemical structure and their broad spectrum of biological properties …

In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones

G Aguirre, L Boiani, H Cerecetto, M Fernández… - Bioorganic & medicinal …, 2004 - Elsevier
The in vitro growth inhibition activity of new thiosemicarbazone derivatives against the
protozoan parasite Trypanosoma cruzi, the causative agent of American trypanosomiasis …

Chemotherapy of Chagas' disease: status and new developments

H Cerecetto, M González - Current topics in medicinal chemistry, 2002 - ingentaconnect.com
Chagas' disease is a major parasitic problem in developing countries in Central and South
America. Chemotherapy for such disease is still insufficient and not effective in its chronic …

Indazole N-oxide derivatives as antiprotozoal agents: Synthesis, biological evaluation and mechanism of action studies

A Gerpe, G Aguirre, L Boiani, H Cerecetto… - Bioorganic & medicinal …, 2006 - Elsevier
A series of indazole N-oxide derivatives have been synthesized and their antichagasic and
leishmanocidal properties studied. 3-Cyano-2-(4-iodophenyl)-2H-indazole N1-oxide …

Synthesis and structure–activity relationship of 3-phenylquinoxaline 1, 4-di-N-oxide derivatives as antimalarial agents

E Vicente, LM Lima, E Bongard, S Charnaud… - European journal of …, 2008 - Elsevier
As a continuation of our research and with the aim of obtaining new antimalarial agents, new
series of 3-phenylquinoxaline 1, 4-di-N-oxide derivatives have been synthesized following …

Imidazolidines as new anti-Trypanosoma cruzi agents: Biological evaluation and structure–activity relationships

MC Caterina, IA Perillo, L Boiani, H Pezaroglo… - Bioorganic & medicinal …, 2008 - Elsevier
Imidazolidine derivatives were studied as anti-Trypanosoma cruzi agents. Imidazolines can
be considered as ethylenediamine/carbonyl precursors and therefore interfere with the …

Novel Antiprotozoal Products: Imidazole and Benzimidazole N‐Oxide Derivatives and Related Compounds

G Aguirre, M Boiani, H Cerecetto… - … der Pharmazie: An …, 2004 - Wiley Online Library
The syntheses and biological evaluation of the first anti‐protozoa imidazole N‐oxide and
benzimidazole N‐oxide and their derivatives are reported. They were tested in vitro against …