Zinc is an essential element required for the function of more than 300 enzymes spanning all
classes. Despite years of dedicated study, questions regarding the connections between …

Metalloenzymes efficiently catalyze some of the most important and difficult reactions in
nature. For many years, coordination chemists have effectively used small molecule models …

The complex formation between cadmium (II) and the ligands cysteine (H2Cys) and
penicillamine (H2Pen= 3, 3′-dimethylcysteine) in aqueous solutions, having C Cd (II)∼ 0.1 …

An important objective of de novo protein design is the preparation of metalloproteins, as
many natural systems contain metals that play crucial roles for the function and/or structural …

Cataract disease results from non-amyloid aggregation of eye lens proteins and is the
leading cause of blindness in the world. A variety of studies have implicated both essential …

We investigate the importance of relativistic effects on NMR shielding constants and
chemical shifts of linear HgL 2 (L= Cl, Br, I, CH 3) compounds using three different relativistic …

De novo metalloprotein design involves the construction of proteins guided by specific
repeat patterns of polar and apolar residues, which, upon self‐assembly, provide a suitable …

Over the past two decades, designed metallopeptides have held the promise for
understanding a variety of fundamental questions in metallobiochemistry; however, these …

Designed metal ion binding peptides offer a variety of applications in both basic science as
model systems of more complex metalloproteins, and in biotechnology, eg in bioremediation …

Complex formation between heavy metal ions and glutathione (GSH) is considered as the
initial step in many detoxification processes in living organisms. In this study the structure …