[HTML][HTML] Update on the epidemiology, genetics, and therapeutic options of hyperuricemia

L Li, Y Zhang, C Zeng - American journal of translational research, 2020 - ncbi.nlm.nih.gov
Hyperuricemia may occur when there is an excess of uric acid in the blood. Hyperuricemia
may result from increased production or decreased excretion of uric acid. Elevated uric acid …

The epidemiology and genetics of hyperuricemia and gout across major racial groups: a literature review and population genetics secondary database analysis

F Butler, A Alghubayshi, Y Roman - Journal of personalized medicine, 2021 - mdpi.com
Gout is an inflammatory condition caused by elevated serum urate (SU), a condition known
as hyperuricemia (HU). Genetic variations, including single nucleotide polymorphisms …

Inulin supplementation ameliorates hyperuricemia and modulates gut microbiota in Uox-knockout mice

Y Guo, Y Yu, H Li, X Ding, X Li, X Jing, J Chen… - European journal of …, 2021 - Springer
Purpose Inulin is a type of fermentable dietary fiber, which is non-digestible, and can
improve metabolic function by modulating intestinal microbiota. This study aimed to evaluate …

Hyperuricemia and its related diseases: mechanisms and advances in therapy

L Du, Y Zong, H Li, Q Wang, L Xie, B Yang… - … and Targeted Therapy, 2024 - nature.com
Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …

Association of impaired sensitivity to thyroid hormones with hyperuricemia through obesity in the euthyroid population

Z Wu, Y Jiang, P Li, Y Wang, H Zhang, Z Li, X Li… - Journal of Translational …, 2023 - Springer
Background Impaired sensitivity to thyroid hormones is a newly proposed clinical entity
associated with hyperuricemia in the subclinical hypothyroid population. However, it is …

Expert consensus for the diagnosis and treatment of patient with hyperuricemia and high cardiovascular risk: 2021 update

C Borghi, J Domienik-Karłowicz, A Tykarski… - Cardiology …, 2021 - journals.viamedica.pl
Uric acid (UA) is the end product of purine metabolism, and its concentration in blood can
increase in humans, great apes, and dalmatian dogs as a consequence of a genetic …

New insight into the management of renal excretion and hyperuricemia: Potential therapeutic strategies with natural bioactive compounds

B Yang, M Xin, S Liang, X Xu, T Cai, L Dong… - Frontiers in …, 2022 - frontiersin.org
Hyperuricemia is the result of increased production and/or underexcretion of uric acid.
Hyperuricemia has been epidemiologically associated with multiple comorbidities, including …

Beneficial properties and mechanisms of natural phytochemicals to combat and prevent hyperuricemia and gout

J Wu, Y Alhamoud, S Lv, F Feng, J Wang - Trends in Food Science & …, 2023 - Elsevier
Background Hyperuricemia refers to a metabolic disorder associated with high serum uric
acid levels and is regarded as a major risk factor not only for the development of gout but …

Real-world treatment of gout and asymptomatic hyperuricemia: a cross-sectional study of Japanese health insurance claims data

R Koto, A Nakajima, H Horiuchi… - Modern …, 2021 - academic.oup.com
Objectives To assess gout and asymptomatic hyperuricemia in Japan and review treatment
conditions. Methods This retrospective cross-sectional study analyzed the prevalence of …

Sex-and age-specific variations, temporal trends and metabolic determinants of serum uric acid concentrations in a large population-based Austrian cohort

E Zitt, A Fischer, K Lhotta, H Concin, G Nagel - Scientific Reports, 2020 - nature.com
Little is known about sex-and age-specific variations and temporal trends in serum uric acid
(SUA) concentrations, the prevalence of hyperuricemia and its association with metabolic …