Adult-Onset Still's Disease (AOSD): Advances in Understanding Pathophysiology, Genetics and Emerging Treatment Options

S Bindoli, C Baggio, A Doria, P Sfriso - Drugs, 2024 - Springer
Adult-onset Still's disease (AOSD) is a multisystemic complex disorder clinically
characterised by episodes of spiking fever, evanescent rash, polyarthritis or diffuse …

A novel pharmaceutical preparation of Tripterygium wilfordii Hook. f. regulates macrophage polarization to alleviate inflammation in rheumatoid arthritis

L Wan, J Liu, C Huang, K Wang… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives To validate the enhanced therapeutic effect of Tripterygium wilfordii Hook.
f.(TWHF) in the treatment of rheumatoid arthritis (RA) by restoring homeostasis of M1/M2 …

A MASsive attack: a pediatric case of macrophage activation syndrome complicated by DIC as an onset of systemic juvenile idiopathic arthritis successfully treated …

A Maeser, M Biernacka-Zielinska… - Rheumatology …, 2024 - Springer
Macrophage activation syndrome (MAS) is one of the most severe complications of systemic
juvenile idiopathic arthritis (sJIA). Around 10% of patients with sJIA exhibit systemic …

Risk of Macrophage Activation Syndrome in Patients with Adult-Onset Still's Disease Treated with IL-1 and IL-6 Inhibitors: A Meta-analysis and Single-Center …

S Adachi, K Takase-Minegishi, A Maeda… - Rheumatology and …, 2023 - Springer
Introduction Patients with adult-onset Still's disease (AOSD) are at risk of developing
macrophage activation syndrome (MAS), a life-threatening condition. Some cases of MAS …

Immunopathology of and potential therapeutics for secondary hemophagocytic lymphohistiocytosis/macrophage activation syndrome: a translational perspective

TTT Nguyen, YT Kim, G Jeong, M Jin - Experimental & Molecular …, 2024 - nature.com
Secondary hemophagocytic lymphohistiocytosis/macrophage activation syndrome
(sHLH/MAS) is a life-threatening immune disorder triggered by rheumatic disease …

Intravenous anakinra for the treatment of haemophagocytic lymphohistiocytosis/macrophage activation syndrome: A systematic review

JEG Charlesworth, A Kavirayani - European Journal of …, 2023 - Wiley Online Library
Background Haemophagocytic lymphohistiocytosis (HLH) or macrophage activation
syndrome (MAS) has a potentially high mortality rate. Anakinra, an interleukin‐1 receptor …

[引用][C] Risk of Macrophage Activation Syndrome in Patients with Adult-Onset Still's Disease Treated with IL-1 and IL-6 Inhibitors: A Meta-analysis and Single-Center …

SAK Takase-Minegishi, A Maeda, HNNHR Yoshimi… - 2023