Extracellular vesicles as signaling mediators and disease biomarkers across biological barriers
Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific
biological information and have progressively emerged as key regulators of organized …
biological information and have progressively emerged as key regulators of organized …
Exosomes: extracellular organelles important in intercellular communication
In addition to intracellular organelles, eukaryotic cells also contain extracellular organelles
that are released, or shed, into the microenvironment. These membranous extracellular …
that are released, or shed, into the microenvironment. These membranous extracellular …
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
Exosomes: proteomic insights and diagnostic potential
Exosomes are 40–100-nm diameter membrane vesicles of endocytic origin that are
released by most cell types upon fusion of multivesicular bodies with the plasma membrane …
released by most cell types upon fusion of multivesicular bodies with the plasma membrane …
Exosomes in cancer liquid biopsy: a focus on breast cancer
The important challenge about cancer is diagnosis in primary stages and proper treatment.
Although classical clinico-pathological features of the tumor have major prognostic value …
Although classical clinico-pathological features of the tumor have major prognostic value …
Mass-spectrometry-based molecular characterization of extracellular vesicles: lipidomics and proteomics
This review discusses extracellular vesicles (EVs), which are submicron-scale, anuclear,
phospholipid bilayer membrane enclosed vesicles that contain lipids, metabolites, proteins …
phospholipid bilayer membrane enclosed vesicles that contain lipids, metabolites, proteins …
Potential utility of liquid biopsy as a diagnostic and prognostic tool for the assessment of solid tumors: implications in the precision oncology
Liquid biopsy is a technique that utilizes circulating biomarkers in the body fluids of cancer
patients to provide information regarding the genetic landscape of the cancer. It is emerging …
patients to provide information regarding the genetic landscape of the cancer. It is emerging …
Major review: Molecular genetics of primary open-angle glaucoma
Y Liu, RR Allingham - Experimental eye research, 2017 - Elsevier
Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
Extracellular vesicles as modulators of wound healing
Impaired healing of cutaneous wounds and ulcers continues to have a major impact on the
quality of life of millions of people. In recent years, the capacity for stem and progenitor cells …
quality of life of millions of people. In recent years, the capacity for stem and progenitor cells …
Roles of exosomes in the normal and diseased eye
M Klingeborn, WM Dismuke, CB Rickman… - Progress in retinal and …, 2017 - Elsevier
Exosomes are nanometer-sized vesicles that are released by cells in a controlled fashion
and mediate a plethora of extra-and intercellular activities. Some key functions of exosomes …
and mediate a plethora of extra-and intercellular activities. Some key functions of exosomes …